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4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.
Wijtmans M, Celanire S, Snip E, Gillard MR, Gelens E, Collart PP, Venhuis BJ, Christophe B, Hulscher S, van der Goot H, Lebon F, Timmerman H, Bakker RA, Lallemand BI, Leurs R, Talaga PE, de Esch IJ. Wijtmans M, et al. Among authors: christophe b. J Med Chem. 2008 May 22;51(10):2944-53. doi: 10.1021/jm7014149. Epub 2008 Apr 24. J Med Chem. 2008. PMID: 18433114
Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
Célanire S, Wijtmans M, Christophe B, Collart P, de Esch I, Dassesse D, Delaunoy C, Denonne F, Durieu V, Gelens E, Gillard M, Lallemand B, Lamberty Y, Lebon F, Nicolas JM, Quéré L, Snip E, Vanbellinghen A, Van Houtvin N, Verbois V, Timmerman H, Talaga P, Leurs R, Provins L. Célanire S, et al. Among authors: christophe b. ChemMedChem. 2009 Jul;4(7):1063-8. doi: 10.1002/cmdc.200900055. ChemMedChem. 2009. PMID: 19405064
Potent anti-muscarinic activity in a novel series of quinuclidine derivatives.
Starck JP, Talaga P, Quéré L, Collart P, Christophe B, Lo Brutto P, Jadot S, Chimmanamada D, Zanda M, Wagner A, Mioskowski C, Massingham R, Guyaux M. Starck JP, et al. Among authors: christophe b. Bioorg Med Chem Lett. 2006 Jan 15;16(2):373-7. doi: 10.1016/j.bmcl.2005.09.079. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275087
Discovery of orally bioavailable NK1 receptor antagonists.
Genicot C, Christophe B, Collart P, Gillard M, Goossens L, Hénichart JP, Lassoie MA, Moureau F, Neuwels M, Nicolas JM, Pasau P, Quéré L, Ryckmans T, Stiernet F, Taverne T, Van Keulen BJ. Genicot C, et al. Among authors: christophe b. Bioorg Med Chem Lett. 2003 Feb 10;13(3):437-42. doi: 10.1016/s0960-894x(02)00956-3. Bioorg Med Chem Lett. 2003. PMID: 12565946
Phenyl-oxazoles, a new family of inverse agonists at the H(3) histamine receptor.
Denonne F, Atienzar F, Célanire S, Christophe B, Delannois F, Delaunoy C, Delporte ML, Durieu V, Gillard M, Lallemand B, Lamberty Y, Lorent G, Vanbellinghen A, Van Houtvin N, Verbois V, Provins L. Denonne F, et al. Among authors: christophe b. ChemMedChem. 2010 Feb 1;5(2):206-12. doi: 10.1002/cmdc.200900446. ChemMedChem. 2010. PMID: 20043314 No abstract available.
75 results