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Page 1
4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.
Wijtmans M, Celanire S, Snip E, Gillard MR, Gelens E, Collart PP, Venhuis BJ, Christophe B, Hulscher S, van der Goot H, Lebon F, Timmerman H, Bakker RA, Lallemand BI, Leurs R, Talaga PE, de Esch IJ. Wijtmans M, et al. Among authors: collart pp. J Med Chem. 2008 May 22;51(10):2944-53. doi: 10.1021/jm7014149. Epub 2008 Apr 24. J Med Chem. 2008. PMID: 18433114
Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
Célanire S, Wijtmans M, Christophe B, Collart P, de Esch I, Dassesse D, Delaunoy C, Denonne F, Durieu V, Gelens E, Gillard M, Lallemand B, Lamberty Y, Lebon F, Nicolas JM, Quéré L, Snip E, Vanbellinghen A, Van Houtvin N, Verbois V, Timmerman H, Talaga P, Leurs R, Provins L. Célanire S, et al. ChemMedChem. 2009 Jul;4(7):1063-8. doi: 10.1002/cmdc.200900055. ChemMedChem. 2009. PMID: 19405064
Potent anti-muscarinic activity in a novel series of quinuclidine derivatives.
Starck JP, Talaga P, Quéré L, Collart P, Christophe B, Lo Brutto P, Jadot S, Chimmanamada D, Zanda M, Wagner A, Mioskowski C, Massingham R, Guyaux M. Starck JP, et al. Bioorg Med Chem Lett. 2006 Jan 15;16(2):373-7. doi: 10.1016/j.bmcl.2005.09.079. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275087
Discovery of orally bioavailable NK1 receptor antagonists.
Genicot C, Christophe B, Collart P, Gillard M, Goossens L, Hénichart JP, Lassoie MA, Moureau F, Neuwels M, Nicolas JM, Pasau P, Quéré L, Ryckmans T, Stiernet F, Taverne T, Van Keulen BJ. Genicot C, et al. Bioorg Med Chem Lett. 2003 Feb 10;13(3):437-42. doi: 10.1016/s0960-894x(02)00956-3. Bioorg Med Chem Lett. 2003. PMID: 12565946
Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists.
Pégurier C, Collart P, Danhaive P, Defays S, Gillard M, Gilson F, Kogej T, Pasau P, Van Houtvin N, Van Thuyne M, van Keulen B. Pégurier C, et al. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4228-31. doi: 10.1016/j.bmcl.2007.05.035. Epub 2007 May 17. Bioorg Med Chem Lett. 2007. PMID: 17532633
Discovery of selective alpha(2C) adrenergic receptor agonists.
Jnoff E, Christophe B, Collart P, Coloretti F, Debeuckelaere A, De Ryck M, Fuks B, Genicot C, Gillard M, Guyaux M, Price N, Vandergeten MC, Vermeiren C. Jnoff E, et al. ChemMedChem. 2012 Mar 5;7(3):385-90. doi: 10.1002/cmdc.201100528. Epub 2012 Jan 19. ChemMedChem. 2012. PMID: 22262529 No abstract available.
Discovery of new C3aR ligands. Part 2: amino-piperidine derivatives.
Denonne F, Binet S, Burton M, Collart P, Defays S, Dipesa A, Eckert M, Giannaras A, Kumar S, Levine B, Nicolas JM, Pasau P, Pégurier C, Preda D, Van houtvin N, Volosov A, Zou D. Denonne F, et al. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3262-5. doi: 10.1016/j.bmcl.2007.04.023. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17459702
Discovery of new C3aR ligands. Part 1: arginine derivatives.
Denonne F, Binet S, Burton M, Collart P, Dipesa A, Ganguly T, Giannaras A, Kumar S, Lewis T, Maounis F, Nicolas JM, Mansley T, Pasau P, Preda D, Stebbins K, Volosov A, Zou D. Denonne F, et al. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3258-61. doi: 10.1016/j.bmcl.2007.04.022. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17467987
Benzyl prolinate derivatives as novel selective KCC2 blockers.
Pégurier C, Bosman N, Collart P, Delporte ML, Leclercq K, Lengelé S, Kanduluru AK, Meunier S, Pacico N, Vadali LR, Wagner A, Wolff C, Provins L. Pégurier C, et al. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2542-5. doi: 10.1016/j.bmcl.2010.02.092. Epub 2010 Mar 1. Bioorg Med Chem Lett. 2010. PMID: 20299216
14 results