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Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.
Monti J, Fischer J, Paskas S, Heinig M, Schulz H, Gösele C, Heuser A, Fischer R, Schmidt C, Schirdewan A, Gross V, Hummel O, Maatz H, Patone G, Saar K, Vingron M, Weldon SM, Lindpaintner K, Hammock BD, Rohde K, Dietz R, Cook SA, Schunck WH, Luft FC, Hubner N. Monti J, et al. Among authors: weldon sm. Nat Genet. 2008 May;40(5):529-37. doi: 10.1038/ng.129. Nat Genet. 2008. PMID: 18443590 Free PMC article.
Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice.
Zhu Y, Blum M, Hoff U, Wesser T, Fechner M, Westphal C, Gürgen D, Catar RA, Philippe A, Wu K, Bubalo G, Rothe M, Weldon SM, Dragun D, Schunck WH. Zhu Y, et al. Among authors: weldon sm. PLoS One. 2016 Jan 4;11(1):e0145645. doi: 10.1371/journal.pone.0145645. eCollection 2016. PLoS One. 2016. PMID: 26727266 Free PMC article.
Vasopressin lowers renal epoxyeicosatrienoic acid levels by activating soluble epoxide hydrolase.
Boldt C, Röschel T, Himmerkus N, Plain A, Bleich M, Labes R, Blum M, Krause H, Magheli A, Giesecke T, Mutig K, Rothe M, Weldon SM, Dragun D, Schunck WH, Bachmann S, Paliege A. Boldt C, et al. Among authors: weldon sm. Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1198-F1210. doi: 10.1152/ajprenal.00062.2016. Epub 2016 Sep 28. Am J Physiol Renal Physiol. 2016. PMID: 27681558 Free article.
GDF11 does not rescue aging-related pathological hypertrophy.
Smith SC, Zhang X, Zhang X, Gross P, Starosta T, Mohsin S, Franti M, Gupta P, Hayes D, Myzithras M, Kahn J, Tanner J, Weldon SM, Khalil A, Guo X, Sabri A, Chen X, MacDonnell S, Houser SR. Smith SC, et al. Among authors: weldon sm. Circ Res. 2015 Nov 6;117(11):926-32. doi: 10.1161/CIRCRESAHA.115.307527. Epub 2015 Sep 17. Circ Res. 2015. PMID: 26383970 Free PMC article.
In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease.
Lin BL, Matera D, Doerner JF, Zheng N, Del Camino D, Mishra S, Bian H, Zeveleva S, Zhen X, Blair NT, Chong JA, Hessler DP, Bedja D, Zhu G, Muller GK, Ranek MJ, Pantages L, McFarland M, Netherton MR, Berry A, Wong D, Rast G, Qian HS, Weldon SM, Kuo JJ, Sauer A, Sarko C, Moran MM, Kass DA, Pullen SS. Lin BL, et al. Among authors: weldon sm. Proc Natl Acad Sci U S A. 2019 May 14;116(20):10156-10161. doi: 10.1073/pnas.1815354116. Epub 2019 Apr 26. Proc Natl Acad Sci U S A. 2019. PMID: 31028142 Free PMC article.
56 results