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A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.
Bouatia-Naji N, Rocheleau G, Van Lommel L, Lemaire K, Schuit F, Cavalcanti-Proença C, Marchand M, Hartikainen AL, Sovio U, De Graeve F, Rung J, Vaxillaire M, Tichet J, Marre M, Balkau B, Weill J, Elliott P, Jarvelin MR, Meyre D, Polychronakos C, Dina C, Sladek R, Froguel P. Bouatia-Naji N, et al. Among authors: lemaire k. Science. 2008 May 23;320(5879):1085-8. doi: 10.1126/science.1156849. Epub 2008 May 1. Science. 2008. PMID: 18451265 Free article.
Why expression of some genes is disallowed in beta-cells.
Quintens R, Hendrickx N, Lemaire K, Schuit F. Quintens R, et al. Among authors: lemaire k. Biochem Soc Trans. 2008 Jun;36(Pt 3):300-5. doi: 10.1042/BST0360300. Biochem Soc Trans. 2008. PMID: 18481946
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.
Bouatia-Naji N, Bonnefond A, Cavalcanti-Proença C, Sparsø T, Holmkvist J, Marchand M, Delplanque J, Lobbens S, Rocheleau G, Durand E, De Graeve F, Chèvre JC, Borch-Johnsen K, Hartikainen AL, Ruokonen A, Tichet J, Marre M, Weill J, Heude B, Tauber M, Lemaire K, Schuit F, Elliott P, Jørgensen T, Charpentier G, Hadjadj S, Cauchi S, Vaxillaire M, Sladek R, Visvikis-Siest S, Balkau B, Lévy-Marchal C, Pattou F, Meyre D, Blakemore AI, Jarvelin MR, Walley AJ, Hansen T, Dina C, Pedersen O, Froguel P. Bouatia-Naji N, et al. Among authors: lemaire k. Nat Genet. 2009 Jan;41(1):89-94. doi: 10.1038/ng.277. Epub 2008 Dec 7. Nat Genet. 2009. PMID: 19060909
Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.
Lemaire K, Ravier MA, Schraenen A, Creemers JW, Van de Plas R, Granvik M, Van Lommel L, Waelkens E, Chimienti F, Rutter GA, Gilon P, in't Veld PA, Schuit FC. Lemaire K, et al. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7. doi: 10.1073/pnas.0906587106. Epub 2009 Aug 18. Proc Natl Acad Sci U S A. 2009. PMID: 19706465 Free PMC article.
Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice.
Colsoul B, Schraenen A, Lemaire K, Quintens R, Van Lommel L, Segal A, Owsianik G, Talavera K, Voets T, Margolskee RF, Kokrashvili Z, Gilon P, Nilius B, Schuit FC, Vennekens R. Colsoul B, et al. Among authors: lemaire k. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5208-13. doi: 10.1073/pnas.0913107107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194741 Free PMC article.
mRNA expression analysis of cell cycle genes in islets of pregnant mice.
Schraenen A, de Faudeur G, Thorrez L, Lemaire K, Van Wichelen G, Granvik M, Van Lommel L, in't Veld P, Schuit F. Schraenen A, et al. Among authors: lemaire k. Diabetologia. 2010 Dec;53(12):2579-88. doi: 10.1007/s00125-010-1912-8. Epub 2010 Oct 1. Diabetologia. 2010. PMID: 20886204 Free PMC article.
55 results