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A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production.
Chung CC, Ohwaki K, Schneeweis JE, Stec E, Varnerin JP, Goudreau PN, Chang A, Cassaday J, Yang L, Yamakawa T, Kornienko O, Hodder P, Inglese J, Ferrer M, Strulovici B, Kusunoki J, Tota MR, Takagi T. Chung CC, et al. Among authors: kusunoki j. Assay Drug Dev Technol. 2008 Jun;6(3):361-74. doi: 10.1089/adt.2007.105. Assay Drug Dev Technol. 2008. PMID: 18452391
Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice.
Harada N, Oda Z, Hara Y, Fujinami K, Okawa M, Ohbuchi K, Yonemoto M, Ikeda Y, Ohwaki K, Aragane K, Tamai Y, Kusunoki J. Harada N, et al. Among authors: kusunoki j. Mol Cell Biol. 2007 Mar;27(5):1881-8. doi: 10.1128/MCB.01122-06. Epub 2007 Jan 8. Mol Cell Biol. 2007. PMID: 17210641 Free PMC article.
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.
Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD. Kim CW, et al. Among authors: kusunoki j. Cell Metab. 2017 Aug 1;26(2):394-406.e6. doi: 10.1016/j.cmet.2017.07.009. Cell Metab. 2017. PMID: 28768177 Free PMC article.
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.
Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD. Kim CW, et al. Among authors: kusunoki j. Cell Metab. 2017 Sep 5;26(3):576. doi: 10.1016/j.cmet.2017.08.011. Cell Metab. 2017. PMID: 28877461 Free article. No abstract available.
ACAT inhibition reduces the progression of preexisting, advanced atherosclerotic mouse lesions without plaque or systemic toxicity.
Rong JX, Blachford C, Feig JE, Bander I, Mayne J, Kusunoki J, Miller C, Davis M, Wilson M, Dehn S, Thorp E, Tabas I, Taubman MB, Rudel LL, Fisher EA. Rong JX, et al. Among authors: kusunoki j. Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):4-12. doi: 10.1161/ATVBAHA.112.252056. Epub 2012 Nov 8. Arterioscler Thromb Vasc Biol. 2013. PMID: 23139293 Free PMC article.
40 results