Kaczorowski GJ - Search Results

1

A high-capacity membrane potential FRET-based assay for the sodium-coupled glucose co-transporter SGLT1.

Weinglass AB, Swensen AM, Liu J, Schmalhofer W, Thomas A, Williams B, Ross L, Hashizume K, Kohler M, Kaczorowski GJ, Garcia ML. Weinglass AB, et al. Among authors: kaczorowski gj. Assay Drug Dev Technol. 2008 Apr;6(2):255-62. doi: 10.1089/adt.2008.125. Assay Drug Dev Technol. 2008. PMID: 18471079

2

Functional assay of voltage-gated sodium channels using membrane potential-sensitive dyes.

Felix JP, Williams BS, Priest BT, Brochu RM, Dick IE, Warren VA, Yan L, Slaughter RS, Kaczorowski GJ, Smith MM, Garcia ML. Felix JP, et al. Among authors: kaczorowski gj. Assay Drug Dev Technol. 2004 Jun;2(3):260-8. doi: 10.1089/1540658041410696. Assay Drug Dev Technol. 2004. PMID: 15285907

3

A high-capacity membrane potential FRET-based assay for NaV1.8 channels.

Liu CJ, Priest BT, Bugianesi RM, Dulski PM, Felix JP, Dick IE, Brochu RM, Knaus HG, Middleton RE, Kaczorowski GJ, Slaughter RS, Garcia ML, Köhler MG. Liu CJ, et al. Among authors: kaczorowski gj. Assay Drug Dev Technol. 2006 Feb;4(1):37-48. doi: 10.1089/adt.2006.4.37. Assay Drug Dev Technol. 2006. PMID: 16506887

4

A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.

Schmalhofer WA, Swensen AM, Thomas BS, Felix JP, Haedo RJ, Solly K, Kiss L, Kaczorowski GJ, Garcia ML. Schmalhofer WA, et al. Among authors: kaczorowski gj. Assay Drug Dev Technol. 2010 Dec;8(6):714-26. doi: 10.1089/adt.2010.0351. Assay Drug Dev Technol. 2010. PMID: 21158686

5

A disubstituted succinamide is a potent sodium channel blocker with efficacy in a rat pain model.

Priest BT, Garcia ML, Middleton RE, Brochu RM, Clark S, Dai G, Dick IE, Felix JP, Liu CJ, Reiseter BS, Schmalhofer WA, Shao PP, Tang YS, Chou MZ, Kohler MG, Smith MM, Warren VA, Williams BS, Cohen CJ, Martin WJ, Meinke PT, Parsons WH, Wafford KA, Kaczorowski GJ. Priest BT, et al. Among authors: kaczorowski gj. Biochemistry. 2004 Aug 3;43(30):9866-76. doi: 10.1021/bi0493259. Biochemistry. 2004. PMID: 15274641

6

Potassium channels as targets for therapeutic intervention.

Garcia ML, Kaczorowski GJ. Garcia ML, et al. Among authors: kaczorowski gj. Sci STKE. 2005 Sep 20;2005(302):pe46. doi: 10.1126/stke.stke.3022005pe46. Sci STKE. 2005. PMID: 16174819 Review.

7

Characterization of Kir1.1 channels with the use of a radiolabeled derivative of tertiapin.

Felix JP, Liu J, Schmalhofer WA, Bailey T, Bednarek MA, Kinkel S, Weinglass AB, Kohler M, Kaczorowski GJ, Priest BT, Garcia ML. Felix JP, et al. Among authors: kaczorowski gj. Biochemistry. 2006 Aug 22;45(33):10129-39. doi: 10.1021/bi060509s. Biochemistry. 2006. PMID: 16906771

8

Ion channel modulators: new targets and new indications for old targets.

Priest B, Kaczorowski GJ, Garcia ML. Priest B, et al. Among authors: kaczorowski gj. Curr Opin Drug Discov Devel. 2006 Sep;9(5):587-94. Curr Opin Drug Discov Devel. 2006. PMID: 17002219 Review.

9

Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7.

Williams BS, Felix JP, Priest BT, Brochu RM, Dai K, Hoyt SB, London C, Tang YS, Duffy JL, Parsons WH, Kaczorowski GJ, Garcia ML. Williams BS, et al. Among authors: kaczorowski gj. Biochemistry. 2007 Dec 18;46(50):14693-703. doi: 10.1021/bi7018207. Epub 2007 Nov 21. Biochemistry. 2007. PMID: 18027973

10

Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake.

Weinglass AB, Köhler MG, Nketiah EO, Liu J, Schmalhofer W, Thomas A, Williams B, Beers L, Smith L, Hafey M, Bleasby K, Leone J, Tang YS, Braun M, Ujjainwalla F, McCann ME, Kaczorowski GJ, Garcia ML. Weinglass AB, et al. Among authors: kaczorowski gj. Mol Pharmacol. 2008 Apr;73(4):1072-84. doi: 10.1124/mol.107.043844. Epub 2008 Jan 10. Mol Pharmacol. 2008. PMID: 18187582

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