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NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer.
Fagerholm R, Hofstetter B, Tommiska J, Aaltonen K, Vrtel R, Syrjäkoski K, Kallioniemi A, Kilpivaara O, Mannermaa A, Kosma VM, Uusitupa M, Eskelinen M, Kataja V, Aittomäki K, von Smitten K, Heikkilä P, Lukas J, Holli K, Bartkova J, Blomqvist C, Bartek J, Nevanlinna H. Fagerholm R, et al. Among authors: lukas j. Nat Genet. 2008 Jul;40(7):844-53. doi: 10.1038/ng.155. Epub 2008 May 30. Nat Genet. 2008. PMID: 18511948
NQO1 expression correlates inversely with NFκB activation in human breast cancer.
Jamshidi M, Bartkova J, Greco D, Tommiska J, Fagerholm R, Aittomäki K, Mattson J, Villman K, Vrtel R, Lukas J, Heikkilä P, Blomqvist C, Bartek J, Nevanlinna H. Jamshidi M, et al. Among authors: lukas j. Breast Cancer Res Treat. 2012 Apr;132(3):955-68. doi: 10.1007/s10549-011-1629-5. Epub 2011 Jun 25. Breast Cancer Res Treat. 2012. PMID: 21706157
CHEK2 variant I157T may be associated with increased breast cancer risk.
Kilpivaara O, Vahteristo P, Falck J, Syrjäkoski K, Eerola H, Easton D, Bartkova J, Lukas J, Heikkilä P, Aittomäki K, Holli K, Blomqvist C, Kallioniemi OP, Bartek J, Nevanlinna H. Kilpivaara O, et al. Among authors: lukas j. Int J Cancer. 2004 Sep 10;111(4):543-7. doi: 10.1002/ijc.20299. Int J Cancer. 2004. PMID: 15239132 Free article.
The DNA damage signalling kinase ATM is aberrantly reduced or lost in BRCA1/BRCA2-deficient and ER/PR/ERBB2-triple-negative breast cancer.
Tommiska J, Bartkova J, Heinonen M, Hautala L, Kilpivaara O, Eerola H, Aittomäki K, Hofstetter B, Lukas J, von Smitten K, Blomqvist C, Ristimäki A, Heikkilä P, Bartek J, Nevanlinna H. Tommiska J, et al. Among authors: lukas j. Oncogene. 2008 Apr 10;27(17):2501-6. doi: 10.1038/sj.onc.1210885. Epub 2007 Nov 5. Oncogene. 2008. PMID: 17982490
DNA repair: New tales of an old tail.
Lukas J, Bartek J. Lukas J, et al. Nature. 2009 Apr 2;458(7238):581-3. doi: 10.1038/458581a. Nature. 2009. PMID: 19340068 No abstract available.
Are all cancer genes equal?
Bartek J, Lukas J. Bartek J, et al. Among authors: lukas j. Nature. 2001 Jun 28;411(6841):1001-2. doi: 10.1038/35082655. Nature. 2001. PMID: 11429580 No abstract available.
DNA repair: Cyclin D1 multitasks.
Bartek J, Lukas J. Bartek J, et al. Among authors: lukas j. Nature. 2011 Jun 8;474(7350):171-2. doi: 10.1038/474171a. Nature. 2011. PMID: 21654798 No abstract available.
DNA repair: Damage alert.
Bartek J, Lukas J. Bartek J, et al. Among authors: lukas j. Nature. 2003 Jan 30;421(6922):486-8. doi: 10.1038/421486a. Nature. 2003. PMID: 12556872 No abstract available.
Cell division: the heart of the cycle.
Lukas J, Bartek J. Lukas J, et al. Nature. 2004 Dec 2;432(7017):564-7. doi: 10.1038/432564a. Nature. 2004. PMID: 15577895 No abstract available.
510 results