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Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist.
J Med Chem. 2008 Jul 10;51(13):3692-5. doi: 10.1021/jm800419w. Epub 2008 Jun 10.
J Med Chem. 2008.
PMID: 18540666
Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels.
Yang ZQ, Barrow JC, Shipe WD, Schlegel KA, Shu Y, Yang FV, Lindsley CW, Rittle KE, Bock MG, Hartman GD, Uebele VN, Nuss CE, Fox SV, Kraus RL, Doran SM, Connolly TM, Tang C, Ballard JE, Kuo Y, Adarayan ED, Prueksaritanont T, Zrada MM, Marino MJ, Graufelds VK, DiLella AG, Reynolds IJ, Vargas HM, Bunting PB, Woltmann RF, Magee MM, Koblan KS, Renger JJ.
Yang ZQ, et al. Among authors: yang fv.
J Med Chem. 2008 Oct 23;51(20):6471-7. doi: 10.1021/jm800830n. Epub 2008 Sep 26.
J Med Chem. 2008.
PMID: 18817368
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Design and synthesis of novel 3-substituted-indole derivatives as selective H3 receptor antagonists and potent free radical scavengers.
Tang L, Zhao L, Hong L, Yang F, Sheng R, Chen J, Shi Y, Zhou N, Hu Y.
Tang L, et al.
Bioorg Med Chem. 2013 Oct 1;21(19):5936-44. doi: 10.1016/j.bmc.2013.07.051. Epub 2013 Aug 8.
Bioorg Med Chem. 2013.
PMID: 23978359
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Synthesis and biological evaluation of new 4β-anilino-4'-O-demethyl-4-desoxypodophyllotoxin derivatives as potential antitumor agents.
Wang L, Yang F, Yang X, Guan X, Hu C, Liu T, He Q, Yang B, Hu Y.
Wang L, et al.
Eur J Med Chem. 2011 Jan;46(1):285-96. doi: 10.1016/j.ejmech.2010.11.016. Epub 2010 Nov 19.
Eur J Med Chem. 2011.
PMID: 21145139
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Parallel synthesis of N-biaryl quinolone carboxylic acids as selective M(1) positive allosteric modulators.
Yang FV, Shipe WD, Bunda JL, Nolt MB, Wisnoski DD, Zhao Z, Barrow JC, Ray WJ, Ma L, Wittmann M, Seager MA, Koeplinger KA, Hartman GD, Lindsley CW.
Yang FV, et al.
Bioorg Med Chem Lett. 2010 Jan 15;20(2):531-6. doi: 10.1016/j.bmcl.2009.11.100. Epub 2009 Nov 24.
Bioorg Med Chem Lett. 2010.
PMID: 20004574
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Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.
Chappie TA, Humphrey JM, Allen MP, Estep KG, Fox CB, Lebel LA, Liras S, Marr ES, Menniti FS, Pandit J, Schmidt CJ, Tu M, Williams RD, Yang FV.
Chappie TA, et al. Among authors: yang fv.
J Med Chem. 2007 Jan 25;50(2):182-5. doi: 10.1021/jm060653b.
J Med Chem. 2007.
PMID: 17228859
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