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Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening.
Schürer SC, Brown SJ, Gonzalez-Cabrera PJ, Schaeffer MT, Chapman J, Jo E, Chase P, Spicer T, Hodder P, Rosen H. Schürer SC, et al. Among authors: gonzalez cabrera pj. ACS Chem Biol. 2008 Aug 15;3(8):486-98. doi: 10.1021/cb800051m. Epub 2008 Jul 1. ACS Chem Biol. 2008. PMID: 18590333 Free PMC article.
Sphingosine 1-phosphate receptor signaling.
Rosen H, Gonzalez-Cabrera PJ, Sanna MG, Brown S. Rosen H, et al. Among authors: gonzalez cabrera pj. Annu Rev Biochem. 2009;78:743-68. doi: 10.1146/annurev.biochem.78.072407.103733. Annu Rev Biochem. 2009. PMID: 19231986 Review.
Actions of a picomolar short-acting S1P₁ agonist in S1P₁-eGFP knock-in mice.
Cahalan SM, Gonzalez-Cabrera PJ, Sarkisyan G, Nguyen N, Schaeffer MT, Huang L, Yeager A, Clemons B, Scott F, Rosen H. Cahalan SM, et al. Among authors: gonzalez cabrera pj. Nat Chem Biol. 2011 May;7(5):254-6. doi: 10.1038/nchembio.547. Epub 2011 Mar 27. Nat Chem Biol. 2011. PMID: 21445057 Free PMC article.
The organization of the sphingosine 1-phosphate signaling system.
Rosen H, Germana Sanna M, Gonzalez-Cabrera PJ, Roberts E. Rosen H, et al. Among authors: gonzalez cabrera pj. Curr Top Microbiol Immunol. 2014;378:1-21. doi: 10.1007/978-3-319-05879-5_1. Curr Top Microbiol Immunol. 2014. PMID: 24728591 Review.
27 results