Jo E - Search Results

1

Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening.

Schürer SC, Brown SJ, Gonzalez-Cabrera PJ, Schaeffer MT, Chapman J, Jo E, Chase P, Spicer T, Hodder P, Rosen H. Schürer SC, et al. Among authors: jo e. ACS Chem Biol. 2008 Aug 15;3(8):486-98. doi: 10.1021/cb800051m. Epub 2008 Jul 1. ACS Chem Biol. 2008. PMID: 18590333 Free PMC article.

2

S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate.

Jo E, Sanna MG, Gonzalez-Cabrera PJ, Thangada S, Tigyi G, Osborne DA, Hla T, Parrill AL, Rosen H. Jo E, et al. Chem Biol. 2005 Jun;12(6):703-15. doi: 10.1016/j.chembiol.2005.04.019. Chem Biol. 2005. PMID: 15975516

3

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

Sanna MG, Wang SK, Gonzalez-Cabrera PJ, Don A, Marsolais D, Matheu MP, Wei SH, Parker I, Jo E, Cheng WC, Cahalan MD, Wong CH, Rosen H. Sanna MG, et al. Among authors: jo e. Nat Chem Biol. 2006 Aug;2(8):434-41. doi: 10.1038/nchembio804. Epub 2006 Jul 9. Nat Chem Biol. 2006. PMID: 16829954

4

Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions.

Gonzalez-Cabrera PJ, Jo E, Sanna MG, Brown S, Leaf N, Marsolais D, Schaeffer MT, Chapman J, Cameron M, Guerrero M, Roberts E, Rosen H. Gonzalez-Cabrera PJ, et al. Among authors: jo e. Mol Pharmacol. 2008 Nov;74(5):1308-18. doi: 10.1124/mol.108.049783. Epub 2008 Aug 15. Mol Pharmacol. 2008. PMID: 18708635 Free PMC article.

5

Novel selective allosteric and bitopic ligands for the S1P(3) receptor.

Jo E, Bhhatarai B, Repetto E, Guerrero M, Riley S, Brown SJ, Kohno Y, Roberts E, Schürer SC, Rosen H. Jo E, et al. ACS Chem Biol. 2012 Dec 21;7(12):1975-83. doi: 10.1021/cb300392z. Epub 2012 Sep 14. ACS Chem Biol. 2012. PMID: 22971058 Free PMC article.

6

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate.

Sanna MG, Liao J, Jo E, Alfonso C, Ahn MY, Peterson MS, Webb B, Lefebvre S, Chun J, Gray N, Rosen H. Sanna MG, et al. Among authors: jo e. J Biol Chem. 2004 Apr 2;279(14):13839-48. doi: 10.1074/jbc.M311743200. Epub 2004 Jan 19. J Biol Chem. 2004. PMID: 14732717 Free article.

7

S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF.

Gon Y, Wood MR, Kiosses WB, Jo E, Sanna MG, Chun J, Rosen H. Gon Y, et al. Among authors: jo e. Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9270-5. doi: 10.1073/pnas.0501997102. Epub 2005 Jun 20. Proc Natl Acad Sci U S A. 2005. PMID: 15968000 Free PMC article. Retracted.

8

Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses.

Wei SH, Rosen H, Matheu MP, Sanna MG, Wang SK, Jo E, Wong CH, Parker I, Cahalan MD. Wei SH, et al. Among authors: jo e. Nat Immunol. 2005 Dec;6(12):1228-35. doi: 10.1038/ni1269. Epub 2005 Nov 6. Nat Immunol. 2005. PMID: 16273098

9

Crystal structure of a lipid G protein-coupled receptor.

Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, Reinhart G, Desale H, Clemons B, Cahalan SM, Schuerer SC, Sanna MG, Han GW, Kuhn P, Rosen H, Stevens RC. Hanson MA, et al. Among authors: jo e. Science. 2012 Feb 17;335(6070):851-5. doi: 10.1126/science.1215904. Science. 2012. PMID: 22344443 Free PMC article.

10

Retraction for "S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF".

Gon Y, Wood MR, Kiosses WB, Jo E, Sanna MG, Chun J, Rosen H. Gon Y, et al. Among authors: jo e. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12561. doi: 10.1073/pnas.0907125106. Epub 2009 Jul 9. Proc Natl Acad Sci U S A. 2009. PMID: 19590011 Free PMC article. No abstract available.

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