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Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein.
Hörkkö S, Miller E, Dudl E, Reaven P, Curtiss LK, Zvaifler NJ, Terkeltaub R, Pierangeli SS, Branch DW, Palinski W, Witztum JL. Hörkkö S, et al. Among authors: witztum jl. J Clin Invest. 1996 Aug 1;98(3):815-25. doi: 10.1172/JCI118854. J Clin Invest. 1996. PMID: 8698874 Free PMC article.
Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo.
Watson AD, Leitinger N, Navab M, Faull KF, Hörkkö S, Witztum JL, Palinski W, Schwenke D, Salomon RG, Sha W, Subbanagounder G, Fogelman AM, Berliner JA. Watson AD, et al. Among authors: witztum jl. J Biol Chem. 1997 May 23;272(21):13597-607. doi: 10.1074/jbc.272.21.13597. J Biol Chem. 1997. PMID: 9153208 Free article.
Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes.
Freigang S, Hörkkö S, Miller E, Witztum JL, Palinski W. Freigang S, et al. Among authors: witztum jl. Arterioscler Thromb Vasc Biol. 1998 Dec;18(12):1972-82. doi: 10.1161/01.atv.18.12.1972. Arterioscler Thromb Vasc Biol. 1998. PMID: 9848892
Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins.
Hörkkö S, Bird DA, Miller E, Itabe H, Leitinger N, Subbanagounder G, Berliner JA, Friedman P, Dennis EA, Curtiss LK, Palinski W, Witztum JL. Hörkkö S, et al. Among authors: witztum jl. J Clin Invest. 1999 Jan;103(1):117-28. doi: 10.1172/JCI4533. J Clin Invest. 1999. PMID: 9884341 Free PMC article.
Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: implications with respect to macrophage recognition of apoptotic cells.
Bird DA, Gillotte KL, Hörkkö S, Friedman P, Dennis EA, Witztum JL, Steinberg D. Bird DA, et al. Among authors: witztum jl. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6347-52. doi: 10.1073/pnas.96.11.6347. Proc Natl Acad Sci U S A. 1999. PMID: 10339590 Free PMC article.
477 results