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Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors.
Bruno V, Battaglia G, Kingston A, O'Neill MJ, Catania MV, Di Grezia R, Nicoletti F. Bruno V, et al. Among authors: battaglia g. Neuropharmacology. 1999 Feb;38(2):199-207. doi: 10.1016/s0028-3908(98)00159-2. Neuropharmacology. 1999. PMID: 10218860
Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors.
Storto M, Capobianco L, Battaglia G, Molinaro G, Gradini R, Riozzi B, Di Mambro A, Mitchell KJ, Bruno V, Vairetti MP, Rutter GA, Nicoletti F. Storto M, et al. Among authors: battaglia g. Mol Pharmacol. 2006 Apr;69(4):1234-41. doi: 10.1124/mol.105.018390. Epub 2006 Jan 19. Mol Pharmacol. 2006. PMID: 16424079
Synergism between fluoxetine and the mGlu2/3 receptor agonist, LY379268, in an in vitro model for antidepressant drug-induced neurogenesis.
Matrisciano F, Zusso M, Panaccione I, Turriziani B, Caruso A, Iacovelli L, Noviello L, Togna G, Melchiorri D, Debetto P, Tatarelli R, Battaglia G, Nicoletti F, Giusti P, Girardi P. Matrisciano F, et al. Among authors: battaglia g. Neuropharmacology. 2008 Feb;54(2):428-37. doi: 10.1016/j.neuropharm.2007.10.020. Epub 2007 Nov 7. Neuropharmacology. 2008. PMID: 18082849
1,011 results