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Extracellular loop C of NPC1L1 is important for binding to ezetimibe.
Weinglass AB, Kohler M, Schulte U, Liu J, Nketiah EO, Thomas A, Schmalhofer W, Williams B, Bildl W, McMasters DR, Dai K, Beers L, McCann ME, Kaczorowski GJ, Garcia ML. Weinglass AB, et al. Among authors: schmalhofer w. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11140-5. doi: 10.1073/pnas.0800936105. Epub 2008 Aug 5. Proc Natl Acad Sci U S A. 2008. PMID: 18682566 Free PMC article.
Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake.
Weinglass AB, Köhler MG, Nketiah EO, Liu J, Schmalhofer W, Thomas A, Williams B, Beers L, Smith L, Hafey M, Bleasby K, Leone J, Tang YS, Braun M, Ujjainwalla F, McCann ME, Kaczorowski GJ, Garcia ML. Weinglass AB, et al. Among authors: schmalhofer w. Mol Pharmacol. 2008 Apr;73(4):1072-84. doi: 10.1124/mol.107.043844. Epub 2008 Jan 10. Mol Pharmacol. 2008. PMID: 18187582
The beta subunit of the high conductance calcium-activated potassium channel. Identification of residues involved in charybdotoxin binding.
Hanner M, Vianna-Jorge R, Kamassah A, Schmalhofer WA, Knaus HG, Kaczorowski GJ, Garcia ML. Hanner M, et al. Among authors: schmalhofer wa. J Biol Chem. 1998 Jun 26;273(26):16289-96. doi: 10.1074/jbc.273.26.16289. J Biol Chem. 1998. PMID: 9632689 Free article.
Coexpression of alpha and beta subunits of the high conductance Ca2+-activated K+ (maxi-K) channel leads to a 50-fold increase in the affinity for 125I-charybdotoxin (125I-ChTX) as compared with when the alpha subunit is expressed alone (Hanner, M., Schmalhofer, W. …
Coexpression of alpha and beta subunits of the high conductance Ca2+-activated K+ (maxi-K) channel leads to a 50-fold increase in the affini …
31 results