Weinglass AB - Search Results

1

Extracellular loop C of NPC1L1 is important for binding to ezetimibe.

Weinglass AB, Kohler M, Schulte U, Liu J, Nketiah EO, Thomas A, Schmalhofer W, Williams B, Bildl W, McMasters DR, Dai K, Beers L, McCann ME, Kaczorowski GJ, Garcia ML. Weinglass AB, et al. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11140-5. doi: 10.1073/pnas.0800936105. Epub 2008 Aug 5. Proc Natl Acad Sci U S A. 2008. PMID: 18682566 Free PMC article.

2

Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake.

Weinglass AB, Köhler MG, Nketiah EO, Liu J, Schmalhofer W, Thomas A, Williams B, Beers L, Smith L, Hafey M, Bleasby K, Leone J, Tang YS, Braun M, Ujjainwalla F, McCann ME, Kaczorowski GJ, Garcia ML. Weinglass AB, et al. Mol Pharmacol. 2008 Apr;73(4):1072-84. doi: 10.1124/mol.107.043844. Epub 2008 Jan 10. Mol Pharmacol. 2008. PMID: 18187582

3

A KV2.1 gating modifier binding assay suitable for high throughput screening.

Schmalhofer WA, Ratliff KS, Weinglass A, Kaczorowski GJ, Garcia ML, Herrington J. Schmalhofer WA, et al. Channels (Austin). 2009 Nov;3(6):437-47. doi: 10.4161/chan.3.6.10201. Channels (Austin). 2009. PMID: 21150283

4

Characterization of Kir1.1 channels with the use of a radiolabeled derivative of tertiapin.

Felix JP, Liu J, Schmalhofer WA, Bailey T, Bednarek MA, Kinkel S, Weinglass AB, Kohler M, Kaczorowski GJ, Priest BT, Garcia ML. Felix JP, et al. Among authors: weinglass ab. Biochemistry. 2006 Aug 22;45(33):10129-39. doi: 10.1021/bi060509s. Biochemistry. 2006. PMID: 16906771

5

A high-capacity membrane potential FRET-based assay for the sodium-coupled glucose co-transporter SGLT1.

Weinglass AB, Swensen AM, Liu J, Schmalhofer W, Thomas A, Williams B, Ross L, Hashizume K, Kohler M, Kaczorowski GJ, Garcia ML. Weinglass AB, et al. Assay Drug Dev Technol. 2008 Apr;6(2):255-62. doi: 10.1089/adt.2008.125. Assay Drug Dev Technol. 2008. PMID: 18471079

6

ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors.

Schmalhofer WA, Calhoun J, Burrows R, Bailey T, Kohler MG, Weinglass AB, Kaczorowski GJ, Garcia ML, Koltzenburg M, Priest BT. Schmalhofer WA, et al. Among authors: weinglass ab. Mol Pharmacol. 2008 Nov;74(5):1476-84. doi: 10.1124/mol.108.047670. Epub 2008 Aug 26. Mol Pharmacol. 2008. PMID: 18728100

7

Technologies for transporter drug discovery.

Weinglass AB, Garcia ML, Kaczorowski GL. Weinglass AB, et al. Channels (Austin). 2008 Sep-Oct;2(5):312-21. doi: 10.4161/chan.2.5.6896. Channels (Austin). 2008. PMID: 18989100 Review.

8

Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation.

Walsh SP, Shahripour A, Tang H, Teumelsan N, Frie J, Zhu Y, Priest BT, Swensen AM, Liu J, Margulis M, Visconti R, Weinglass A, Felix JP, Brochu RM, Bailey T, Thomas-Fowlkes B, Alonso-Galicia M, Zhou X, Pai LY, Corona A, Hampton C, Hernandez M, Bentley R, Chen J, Shah K, Metzger J, Forrest M, Owens K, Tong V, Ha S, Roy S, Kaczorowski GJ, Yang L, Parmee E, Garcia ML, Sullivan K, Pasternak A. Walsh SP, et al. ACS Med Chem Lett. 2015 May 7;6(7):747-52. doi: 10.1021/ml500440u. eCollection 2015 Jul 9. ACS Med Chem Lett. 2015. PMID: 26191360 Free PMC article.

9

The central cytoplasmic loop of the major facilitator superfamily of transport proteins governs efficient membrane insertion.

Weinglass AB, Kaback HR. Weinglass AB, et al. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8938-43. doi: 10.1073/pnas.140224497. Proc Natl Acad Sci U S A. 2000. PMID: 10880570 Free PMC article.

10

Engineering a terbium-binding site into an integral membrane protein for luminescence energy transfer.

Vázquez-Ibar JL, Weinglass AB, Kaback HR. Vázquez-Ibar JL, et al. Among authors: weinglass ab. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3487-92. doi: 10.1073/pnas.052703599. Epub 2002 Mar 12. Proc Natl Acad Sci U S A. 2002. PMID: 11891311 Free PMC article.

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