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Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1): randomized, double-blind, placebo-controlled phase 2 dose-finding trial.
Macdonald RL, Kassell NF, Mayer S, Ruefenacht D, Schmiedek P, Weidauer S, Frey A, Roux S, Pasqualin A; CONSCIOUS-1 Investigators. Macdonald RL, et al. Among authors: schmiedek p. Stroke. 2008 Nov;39(11):3015-21. doi: 10.1161/STROKEAHA.108.519942. Epub 2008 Aug 7. Stroke. 2008. PMID: 18688013 Clinical Trial.
Effect of nicardipine prolonged-release implants on cerebral vasospasm and clinical outcome after severe aneurysmal subarachnoid hemorrhage: a prospective, randomized, double-blind phase IIa study.
Barth M, Capelle HH, Weidauer S, Weiss C, Münch E, Thomé C, Luecke T, Schmiedek P, Kasuya H, Vajkoczy P. Barth M, et al. Among authors: schmiedek p. Stroke. 2007 Feb;38(2):330-6. doi: 10.1161/01.STR.0000254601.74596.0f. Epub 2006 Dec 21. Stroke. 2007. PMID: 17185636 Clinical Trial.
Double-blind, randomized, vehicle-controlled study of high-dose tirilazad mesylate in women with aneurysmal subarachnoid hemorrhage. Part I. A cooperative study in Europe, Australia, New Zealand, and South Africa.
Lanzino G, Kassell NF, Dorsch NW, Pasqualin A, Brandt L, Schmiedek P, Truskowski LL, Alves WM. Lanzino G, et al. Among authors: schmiedek p. J Neurosurg. 1999 Jun;90(6):1011-7. doi: 10.3171/jns.1999.90.6.1011. J Neurosurg. 1999. PMID: 10350245 Clinical Trial.
Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: results of a randomized, double-blind, placebo-controlled, multicenter phase IIa study.
Vajkoczy P, Meyer B, Weidauer S, Raabe A, Thome C, Ringel F, Breu V, Schmiedek P. Vajkoczy P, et al. Among authors: schmiedek p. J Neurosurg. 2005 Jul;103(1):9-17. doi: 10.3171/jns.2005.103.1.0009. J Neurosurg. 2005. PMID: 16121967 Clinical Trial.
161 results