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p38 mitogen-activated protein kinase stimulates estrogen-mediated transcription and proliferation through the phosphorylation and potentiation of the p160 coactivator glucocorticoid receptor-interacting protein 1.
Frigo DE, Basu A, Nierth-Simpson EN, Weldon CB, Dugan CM, Elliott S, Collins-Burow BM, Salvo VA, Zhu Y, Melnik LI, Lopez GN, Kushner PJ, Curiel TJ, Rowan BG, McLachlan JA, Burow ME. Frigo DE, et al. Among authors: rowan bg. Mol Endocrinol. 2006 May;20(5):971-83. doi: 10.1210/me.2004-0075. Epub 2006 Jan 12. Mol Endocrinol. 2006. PMID: 16410316
Gαo potentiates estrogen receptor α activity via the ERK signaling pathway.
Bratton MR, Antoon JW, Duong BN, Frigo DE, Tilghman S, Collins-Burow BM, Elliott S, Tang Y, Melnik LI, Lai L, Alam J, Beckman BS, Hill SM, Rowan BG, McLachlan JA, Burow ME. Bratton MR, et al. J Endocrinol. 2012 Jul;214(1):45-54. doi: 10.1530/JOE-12-0097. Epub 2012 May 4. J Endocrinol. 2012. PMID: 22562654 Free PMC article.
Stable inhibition of specific estrogen receptor α (ERα) phosphorylation confers increased growth, migration/invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells.
Huderson BP, Duplessis TT, Williams CC, Seger HC, Marsden CG, Pouey KJ, Hill SM, Rowan BG. Huderson BP, et al. Among authors: rowan bg. Endocrinology. 2012 Sep;153(9):4144-59. doi: 10.1210/en.2011-2001. Epub 2012 Jun 25. Endocrinology. 2012. PMID: 22733972 Free PMC article.
151 results