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The antidepressant sertraline downregulates Akt and has activity against melanoma cells.
Reddy KK, Lefkove B, Chen LB, Govindarajan B, Carracedo A, Velasco G, Carrillo CO, Bhandarkar SS, Owens MJ, Mechta-Grigoriou F, Arbiser JL. Reddy KK, et al. Among authors: bhandarkar ss. Pigment Cell Melanoma Res. 2008 Aug;21(4):451-6. doi: 10.1111/j.1755-148X.2008.00481.x. Pigment Cell Melanoma Res. 2008. PMID: 18710373
Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice.
Perry BN, Govindarajan B, Bhandarkar SS, Knaus UG, Valo M, Sturk C, Carrillo CO, Sohn A, Cerimele F, Dumont D, Losken A, Williams J, Brown LF, Tan X, Ioffe E, Yancopoulos GD, Arbiser JL. Perry BN, et al. Among authors: bhandarkar ss. J Invest Dermatol. 2006 Oct;126(10):2316-22. doi: 10.1038/sj.jid.5700413. Epub 2006 Jun 1. J Invest Dermatol. 2006. PMID: 16741507 Free article.
Curcumin as an inhibitor of angiogenesis.
Bhandarkar SS, Arbiser JL. Bhandarkar SS, et al. Adv Exp Med Biol. 2007;595:185-95. doi: 10.1007/978-0-387-46401-5_7. Adv Exp Med Biol. 2007. PMID: 17569211 Review.
Efficacy of rapamycin in scleroderma: a case study.
Fried L, Kirsner RS, Bhandarkar S, Arbiser JL. Fried L, et al. Lymphat Res Biol. 2008;6(3-4):217-9. doi: 10.1089/lrb.2008.1006. Lymphat Res Biol. 2008. PMID: 18950288 Free PMC article.
Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.
Bhandarkar SS, Jaconi M, Fried LE, Bonner MY, Lefkove B, Govindarajan B, Perry BN, Parhar R, Mackelfresh J, Sohn A, Stouffs M, Knaus U, Yancopoulos G, Reiss Y, Benest AV, Augustin HG, Arbiser JL. Bhandarkar SS, et al. J Clin Invest. 2009 Aug;119(8):2359-65. doi: 10.1172/JCI33877. Epub 2009 Jul 13. J Clin Invest. 2009. PMID: 19620773 Free PMC article.
13 results