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MLH1 -93G>A promoter polymorphism and risk of mismatch repair deficient colorectal cancer.
Allan JM, Shorto J, Adlard J, Bury J, Coggins R, George R, Katory M, Quirke P, Richman S, Scott D, Scott K, Seymour M, Travis LB, Worrillow LJ, Bishop DT, Cox A; UK NCRI Colorectal Clinical Studies Group; Colorectal Cancer Study Group. Allan JM, et al. Among authors: seymour m. Int J Cancer. 2008 Nov 15;123(10):2456-9. doi: 10.1002/ijc.23770. Int J Cancer. 2008. PMID: 18712731 Free article.
Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis.
Smith CG, West H, Harris R, Idziaszczyk S, Maughan TS, Kaplan R, Richman S, Quirke P, Seymour M, Moskvina V, Steinke V, Propping P, Hes FJ, Wijnen J, Cheadle JP. Smith CG, et al. Among authors: seymour m. J Natl Cancer Inst. 2013 Aug 21;105(16):1249-53. doi: 10.1093/jnci/djt183. Epub 2013 Jul 12. J Natl Cancer Inst. 2013. PMID: 23852950
A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan & Ciclosporin in COLOrectal cancer therapy trial (PICCOLO).
Middleton G, Brown S, Lowe C, Maughan T, Gwyther S, Oliver A, Richman S, Blake D, Napp V, Marshall H, Wadsley J, Maisey N, Chau I, Hill M, Gollins S, Myint S, Slater S, Wagstaff J, Bridgewater J, Seymour M. Middleton G, et al. Among authors: seymour m. Eur J Cancer. 2013 Nov;49(16):3507-16. doi: 10.1016/j.ejca.2013.06.017. Epub 2013 Aug 13. Eur J Cancer. 2013. PMID: 23953030 Clinical Trial.
Response.
Smith CG, West H, Harris R, Idziaszczyk S, Maughan TS, Kaplan R, Richman S, Quirke P, Seymour M, Moskvina V, Steinke V, Propping P, Hes FJ, Wijnen J, Cheadle JP. Smith CG, et al. Among authors: seymour m. J Natl Cancer Inst. 2014 Apr 26;106(5):dju087. doi: 10.1093/jnci/dju087. J Natl Cancer Inst. 2014. PMID: 24771876 No abstract available.
Analyses of 7,635 Patients with Colorectal Cancer Using Independent Training and Validation Cohorts Show That rs9929218 in CDH1 Is a Prognostic Marker of Survival.
Smith CG, Fisher D, Harris R, Maughan TS, Phipps AI, Richman S, Seymour M, Tomlinson I, Rosmarin D, Kerr D, Chan AT, Peters U, Newcomb PA, Idziaszczyk S, West H, Meade A, Kaplan R, Cheadle JP. Smith CG, et al. Among authors: seymour m. Clin Cancer Res. 2015 Aug 1;21(15):3453-61. doi: 10.1158/1078-0432.CCR-14-3136. Epub 2015 Apr 14. Clin Cancer Res. 2015. PMID: 25873087 Free PMC article.
HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials.
Richman SD, Southward K, Chambers P, Cross D, Barrett J, Hemmings G, Taylor M, Wood H, Hutchins G, Foster JM, Oumie A, Spink KG, Brown SR, Jones M, Kerr D, Handley K, Gray R, Seymour M, Quirke P. Richman SD, et al. Among authors: seymour m. J Pathol. 2016 Mar;238(4):562-70. doi: 10.1002/path.4679. Epub 2016 Jan 29. J Pathol. 2016. PMID: 26690310 Free PMC article.
Intratumoral stromal morphometry predicts disease recurrence but not response to 5-fluorouracil-results from the QUASAR trial of colorectal cancer.
Hutchins GGA, Treanor D, Wright A, Handley K, Magill L, Tinkler-Hundal E, Southward K, Seymour M, Kerr D, Gray R, Quirke P; QUASAR trial collaborators and the UK National Cancer Research Institute Colorectal Cancer Clinical Studies Group. Hutchins GGA, et al. Among authors: seymour m. Histopathology. 2018 Feb;72(3):391-404. doi: 10.1111/his.13326. Epub 2017 Nov 27. Histopathology. 2018. PMID: 28746977 Free article. Clinical Trial.
Clinical and molecular characteristics and treatment outcomes of advanced right-colon, left-colon and rectal cancers: data from 1180 patients in a phase III trial of panitumumab with an extended biomarker panel.
Seligmann JF, Elliott F, Richman S, Hemmings G, Brown S, Jacobs B, Williams C, Tejpar S, Barrett JH, Quirke P, Seymour M. Seligmann JF, et al. Among authors: seymour m. Ann Oncol. 2020 Aug;31(8):1021-1029. doi: 10.1016/j.annonc.2020.04.476. Epub 2020 May 6. Ann Oncol. 2020. PMID: 32387453 Free article. Clinical Trial.
380 results