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Human bone marrow hosts polyfunctional memory CD4+ and CD8+ T cells with close contact to IL-15-producing cells.
Herndler-Brandstetter D, Landgraf K, Jenewein B, Tzankov A, Brunauer R, Brunner S, Parson W, Kloss F, Gassner R, Lepperdinger G, Grubeck-Loebenstein B. Herndler-Brandstetter D, et al. Among authors: lepperdinger g. J Immunol. 2011 Jun 15;186(12):6965-71. doi: 10.4049/jimmunol.1100243. Epub 2011 May 11. J Immunol. 2011. PMID: 21562158 Free article.
The impact of aging on memory T cell phenotype and function in the human bone marrow.
Herndler-Brandstetter D, Landgraf K, Tzankov A, Jenewein B, Brunauer R, Laschober GT, Parson W, Kloss F, Gassner R, Lepperdinger G, Grubeck-Loebenstein B. Herndler-Brandstetter D, et al. Among authors: lepperdinger g. J Leukoc Biol. 2012 Feb;91(2):197-205. doi: 10.1189/jlb.0611299. Epub 2011 Oct 19. J Leukoc Biol. 2012. PMID: 22013229
CD25-expressing CD8+ T cells are potent memory cells in old age.
Herndler-Brandstetter D, Schwaiger S, Veel E, Fehrer C, Cioca DP, Almanzar G, Keller M, Pfister G, Parson W, Würzner R, Schönitzer D, Henson SM, Aspinall R, Lepperdinger G, Grubeck-Loebenstein B. Herndler-Brandstetter D, et al. Among authors: lepperdinger g. J Immunol. 2005 Aug 1;175(3):1566-74. doi: 10.4049/jimmunol.175.3.1566. J Immunol. 2005. PMID: 16034095
miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging.
Hackl M, Brunner S, Fortschegger K, Schreiner C, Micutkova L, Mück C, Laschober GT, Lepperdinger G, Sampson N, Berger P, Herndler-Brandstetter D, Wieser M, Kühnel H, Strasser A, Rinnerthaler M, Breitenbach M, Mildner M, Eckhart L, Tschachler E, Trost A, Bauer JW, Papak C, Trajanoski Z, Scheideler M, Grillari-Voglauer R, Grubeck-Loebenstein B, Jansen-Dürr P, Grillari J. Hackl M, et al. Among authors: lepperdinger g. Aging Cell. 2010 Apr;9(2):291-6. doi: 10.1111/j.1474-9726.2010.00549.x. Epub 2010 Jan 18. Aging Cell. 2010. PMID: 20089119 Free PMC article.
Identification of evolutionarily conserved genetic regulators of cellular aging.
Laschober GT, Ruli D, Hofer E, Muck C, Carmona-Gutierrez D, Ring J, Hutter E, Ruckenstuhl C, Micutkova L, Brunauer R, Jamnig A, Trimmel D, Herndler-Brandstetter D, Brunner S, Zenzmaier C, Sampson N, Breitenbach M, Fröhlich KU, Grubeck-Loebenstein B, Berger P, Wieser M, Grillari-Voglauer R, Thallinger GG, Grillari J, Trajanoski Z, Madeo F, Lepperdinger G, Jansen-Dürr P. Laschober GT, et al. Among authors: lepperdinger g. Aging Cell. 2010 Dec;9(6):1084-97. doi: 10.1111/j.1474-9726.2010.00637.x. Epub 2010 Oct 28. Aging Cell. 2010. PMID: 20883526 Free PMC article.
Post-thymic regulation of CD5 levels in human memory T cells is inversely associated with the strength of responsiveness to interleukin-15.
Herndler-Brandstetter D, Brunner S, Weiskopf D, van Rijn R, Landgraf K, Dejaco C, Duftner C, Schirmer M, Kloss F, Gassner R, Lepperdinger G, Grubeck-Loebenstein B. Herndler-Brandstetter D, et al. Among authors: lepperdinger g. Hum Immunol. 2011 Aug;72(8):627-31. doi: 10.1016/j.humimm.2011.03.028. Epub 2011 Apr 15. Hum Immunol. 2011. PMID: 21539877 Free PMC article.
83 results