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Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy.
Karpanen T, Bry M, Ollila HM, Seppänen-Laakso T, Liimatta E, Leskinen H, Kivelä R, Helkamaa T, Merentie M, Jeltsch M, Paavonen K, Andersson LC, Mervaala E, Hassinen IE, Ylä-Herttuala S, Oresic M, Alitalo K. Karpanen T, et al. Among authors: andersson lc. Circ Res. 2008 Oct 24;103(9):1018-26. doi: 10.1161/CIRCRESAHA.108.178459. Epub 2008 Aug 28. Circ Res. 2008. PMID: 18757827 Free PMC article.
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype.
Petrova TV, Nykänen A, Norrmén C, Ivanov KI, Andersson LC, Haglund C, Puolakkainen P, Wempe F, von Melchner H, Gradwohl G, Vanharanta S, Aaltonen LA, Saharinen J, Gentile M, Clarke A, Taipale J, Oliver G, Alitalo K. Petrova TV, et al. Among authors: andersson lc. Cancer Cell. 2008 May;13(5):407-19. doi: 10.1016/j.ccr.2008.02.020. Cancer Cell. 2008. PMID: 18455124 Free article.
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation.
Bry M, Kivelä R, Holopainen T, Anisimov A, Tammela T, Soronen J, Silvola J, Saraste A, Jeltsch M, Korpisalo P, Carmeliet P, Lemström KB, Shibuya M, Ylä-Herttuala S, Alhonen L, Mervaala E, Andersson LC, Knuuti J, Alitalo K. Bry M, et al. Among authors: andersson lc. Circulation. 2010 Oct 26;122(17):1725-33. doi: 10.1161/CIRCULATIONAHA.110.957332. Epub 2010 Oct 11. Circulation. 2010. PMID: 20937974
Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth.
Holopainen T, López-Alpuche V, Zheng W, Heljasvaara R, Jones D, He Y, Tvorogov D, D'Amico G, Wiener Z, Andersson LC, Pihlajaniemi T, Min W, Alitalo K. Holopainen T, et al. Among authors: andersson lc. Cancer Res. 2012 Jul 15;72(14):3512-21. doi: 10.1158/0008-5472.CAN-11-1070. Epub 2012 May 16. Cancer Res. 2012. PMID: 22593188
Endothelial Bmx tyrosine kinase activity is essential for myocardial hypertrophy and remodeling.
Holopainen T, Räsänen M, Anisimov A, Tuomainen T, Zheng W, Tvorogov D, Hulmi JJ, Andersson LC, Cenni B, Tavi P, Mervaala E, Kivelä R, Alitalo K. Holopainen T, et al. Among authors: andersson lc. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13063-8. doi: 10.1073/pnas.1517810112. Epub 2015 Oct 1. Proc Natl Acad Sci U S A. 2015. PMID: 26430242 Free PMC article.
360 results