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Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels.
J Med Chem. 2008 Oct 23;51(20):6471-7. doi: 10.1021/jm800830n. Epub 2008 Sep 26.
J Med Chem. 2008.
PMID: 18817368
Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist.
Shipe WD, Barrow JC, Yang ZQ, Lindsley CW, Yang FV, Schlegel KA, Shu Y, Rittle KE, Bock MG, Hartman GD, Tang C, Ballard JE, Kuo Y, Adarayan ED, Prueksaritanont T, Zrada MM, Uebele VN, Nuss CE, Connolly TM, Doran SM, Fox SV, Kraus RL, Marino MJ, Graufelds VK, Vargas HM, Bunting PB, Hasbun-Manning M, Evans RM, Koblan KS, Renger JJ.
Shipe WD, et al. Among authors: yang fv.
J Med Chem. 2008 Jul 10;51(13):3692-5. doi: 10.1021/jm800419w. Epub 2008 Jun 10.
J Med Chem. 2008.
PMID: 18540666
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Design and synthesis of novel 3-substituted-indole derivatives as selective H3 receptor antagonists and potent free radical scavengers.
Tang L, Zhao L, Hong L, Yang F, Sheng R, Chen J, Shi Y, Zhou N, Hu Y.
Tang L, et al.
Bioorg Med Chem. 2013 Oct 1;21(19):5936-44. doi: 10.1016/j.bmc.2013.07.051. Epub 2013 Aug 8.
Bioorg Med Chem. 2013.
PMID: 23978359
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Synthesis and biological evaluation of new 4β-anilino-4'-O-demethyl-4-desoxypodophyllotoxin derivatives as potential antitumor agents.
Wang L, Yang F, Yang X, Guan X, Hu C, Liu T, He Q, Yang B, Hu Y.
Wang L, et al.
Eur J Med Chem. 2011 Jan;46(1):285-96. doi: 10.1016/j.ejmech.2010.11.016. Epub 2010 Nov 19.
Eur J Med Chem. 2011.
PMID: 21145139
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Identification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptor.
Shi Y, Sheng R, Zhong T, Xu Y, Chen X, Yang D, Sun Y, Yang F, Hu Y, Zhou N.
Shi Y, et al.
PLoS One. 2012;7(8):e42185. doi: 10.1371/journal.pone.0042185. Epub 2012 Aug 1.
PLoS One. 2012.
PMID: 22870296
Free PMC article.
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Parallel synthesis of N-biaryl quinolone carboxylic acids as selective M(1) positive allosteric modulators.
Yang FV, Shipe WD, Bunda JL, Nolt MB, Wisnoski DD, Zhao Z, Barrow JC, Ray WJ, Ma L, Wittmann M, Seager MA, Koeplinger KA, Hartman GD, Lindsley CW.
Yang FV, et al.
Bioorg Med Chem Lett. 2010 Jan 15;20(2):531-6. doi: 10.1016/j.bmcl.2009.11.100. Epub 2009 Nov 24.
Bioorg Med Chem Lett. 2010.
PMID: 20004574
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Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.
Chappie TA, Humphrey JM, Allen MP, Estep KG, Fox CB, Lebel LA, Liras S, Marr ES, Menniti FS, Pandit J, Schmidt CJ, Tu M, Williams RD, Yang FV.
Chappie TA, et al. Among authors: yang fv.
J Med Chem. 2007 Jan 25;50(2):182-5. doi: 10.1021/jm060653b.
J Med Chem. 2007.
PMID: 17228859
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