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Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.
Koh AS, Kuo AJ, Park SY, Cheung P, Abramson J, Bua D, Carney D, Shoelson SE, Gozani O, Kingston RE, Benoist C, Mathis D. Koh AS, et al. Among authors: gozani o. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15878-83. doi: 10.1073/pnas.0808470105. Epub 2008 Oct 7. Proc Natl Acad Sci U S A. 2008. PMID: 18840680 Free PMC article.
Functional epigenomics: chromatin complexity untangled.
Mack R, Gozani O. Mack R, et al. Among authors: gozani o. Nat Struct Mol Biol. 2023 Oct;30(10):1403-1405. doi: 10.1038/s41594-023-01088-3. Nat Struct Mol Biol. 2023. PMID: 37684554 Free PMC article.
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.
Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Peña P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, Ayer DE, Kutateladze TG, Shi Y, Côté J, Chua KF, Gozani O. Shi X, et al. Among authors: gozani o. Nature. 2006 Jul 6;442(7098):96-9. doi: 10.1038/nature04835. Epub 2006 May 21. Nature. 2006. PMID: 16728974 Free PMC article.
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.
Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA. Matthews AG, et al. Among authors: gozani o. Nature. 2007 Dec 13;450(7172):1106-10. doi: 10.1038/nature06431. Epub 2007 Nov 21. Nature. 2007. PMID: 18033247 Free PMC article.
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin.
Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF. Michishita E, et al. Among authors: gozani o. Nature. 2008 Mar 27;452(7186):492-6. doi: 10.1038/nature06736. Epub 2008 Mar 12. Nature. 2008. PMID: 18337721 Free PMC article.
123 results