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Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice.
Mårtensson UE, Salehi SA, Windahl S, Gomez MF, Swärd K, Daszkiewicz-Nilsson J, Wendt A, Andersson N, Hellstrand P, Grände PO, Owman C, Rosen CJ, Adamo ML, Lundquist I, Rorsman P, Nilsson BO, Ohlsson C, Olde B, Leeb-Lundberg LM. Mårtensson UE, et al. Endocrinology. 2009 Feb;150(2):687-98. doi: 10.1210/en.2008-0623. Epub 2008 Oct 9. Endocrinology. 2009. PMID: 18845638
Ligand-Independent G Protein-Coupled Estrogen Receptor/G Protein-Coupled Receptor 30 Activity: Lack of Receptor-Dependent Effects of G-1 and 17β-Estradiol.
Tutzauer J, Gonzalez de Valdivia E, Swärd K, Alexandrakis Eilard I, Broselid S, Kahn R, Olde B, Leeb-Lundberg LMF. Tutzauer J, et al. Among authors: leeb lundberg lmf. Mol Pharmacol. 2021 Sep;100(3):271-282. doi: 10.1124/molpharm.121.000259. Epub 2021 Jul 30. Mol Pharmacol. 2021. PMID: 34330822 Free PMC article.
G protein-coupled estrogen receptor is apoptotic and correlates with increased distant disease-free survival of estrogen receptor-positive breast cancer patients.
Broselid S, Cheng B, Sjöström M, Lövgren K, Klug-De Santiago HL, Belting M, Jirström K, Malmström P, Olde B, Bendahl PO, Hartman L, Fernö M, Leeb-Lundberg LM. Broselid S, et al. Clin Cancer Res. 2013 Apr 1;19(7):1681-92. doi: 10.1158/1078-0432.CCR-12-2376. Clin Cancer Res. 2013. PMID: 23554355
85 results