Matthews J - Search Results

1

Improvement of dyslipidemia, insulin sensitivity, and energy balance by a peroxisome proliferator-activated receptor alpha agonist.

Chen X, Matthews J, Zhou L, Pelton P, Liang Y, Xu J, Yang M, Cryan E, Rybczynski P, Demarest K. Chen X, et al. Among authors: matthews j. Metabolism. 2008 Nov;57(11):1516-25. doi: 10.1016/j.metabol.2008.06.005. Metabolism. 2008. PMID: 18940388

2

Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARalpha agonists.

Matthews JM, Chen X, Cryan E, Hlasta DJ, Rybczynski PJ, Strauss K, Tang Y, Xu JZ, Yang M, Zhou L, Demarest KT. Matthews JM, et al. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6773-8. doi: 10.1016/j.bmcl.2007.10.041. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 18029176

3

Discovery of a dihydropyrimidine series of molecules that selectively mimic the biological actions of calcitonin.

Matthews JM, Liotta F, Hageman W, Rivero RA, Westover L, Yang M, Xu J, Demarest K. Matthews JM, et al. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1155-9. doi: 10.1016/j.bmcl.2003.12.071. Bioorg Med Chem Lett. 2004. PMID: 14980655

4

Characterization of RWJ-351647, a novel nonpeptide vasopressin V2 receptor antagonist.

Gunnet JW, Matthews JM, Maryanoff BE, de Garavilla L, Andrade-Gordon P, Damiano B, Hageman W, Look R, Stahle P, Streeter AJ, Wines PG, Demarest KT. Gunnet JW, et al. Among authors: matthews jm. Clin Exp Pharmacol Physiol. 2006 Apr;33(4):320-6. doi: 10.1111/j.1440-1681.2006.04369.x. Clin Exp Pharmacol Physiol. 2006. PMID: 16620295

5

Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templates.

Matthews JM, Hoekstra WJ, Dyatkin AB, Hecker LR, Hlasta DJ, Poulter BL, Andrade-Gordon P, de Garavilla L, Demarest KT, Ericson E, Gunnet JW, Hageman W, Look R, Moore JB, Reynolds CH, Maryanoff BE. Matthews JM, et al. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2747-52. doi: 10.1016/j.bmcl.2004.03.083. Bioorg Med Chem Lett. 2004. PMID: 15125926

6

Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists.

Matthews JM, Greco MN, Hecker LR, Hoekstra WJ, Andrade-Gordon P, de Garavilla L, Demarest KT, Ericson E, Gunnet JW, Hageman W, Look R, Moore JB, Maryanoff BE. Matthews JM, et al. Bioorg Med Chem Lett. 2003 Feb 24;13(4):753-6. doi: 10.1016/s0960-894x(02)01059-4. Bioorg Med Chem Lett. 2003. PMID: 12639574

7

Tetrahydroindazole derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists.

Matthews JM, McNally JJ, Connolly PJ, Xia M, Zhu B, Black S, Chen C, Hou C, Liang Y, Tang Y, Macielag MJ. Matthews JM, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5346-5349. doi: 10.1016/j.bmcl.2016.09.025. Epub 2016 Sep 10. Bioorg Med Chem Lett. 2016. PMID: 27671496

8

Tetrahydropyrazolo[4,3-c]pyridine derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists.

Zhu B, Matthews JM, Xia M, Black S, Chen C, Hou C, Liang Y, Tang Y, Macielag MJ. Zhu B, et al. Among authors: matthews jm. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5597-5601. doi: 10.1016/j.bmcl.2016.09.026. Epub 2016 Sep 12. Bioorg Med Chem Lett. 2016. PMID: 27671499

9

Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists.

Zhu B, Xia M, Xu X, Ludovici DW, Tennakoon M, Youngman MA, Matthews JM, Dax SL, Colburn RW, Qin N, Hutchinson TL, Lubin ML, Brandt MR, Stone DJ, Flores CM, Macielag MJ. Zhu B, et al. Among authors: matthews jm. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2234-7. doi: 10.1016/j.bmcl.2013.01.062. Epub 2013 Feb 4. Bioorg Med Chem Lett. 2013. PMID: 23411075

10

The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists.

Matthews JM, Qin N, Colburn RW, Dax SL, Hawkins M, McNally JJ, Reany L, Youngman MA, Baker J, Hutchinson T, Liu Y, Lubin ML, Neeper M, Brandt MR, Stone DJ, Flores CM. Matthews JM, et al. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2922-6. doi: 10.1016/j.bmcl.2012.02.060. Epub 2012 Feb 27. Bioorg Med Chem Lett. 2012. PMID: 22421018

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