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Cauliflower mosaic virus gene VI product N-terminus contains regions involved in resistance-breakage, self-association and interactions with movement protein.
Hapiak M, Li Y, Agama K, Swade S, Okenka G, Falk J, Khandekar S, Raikhy G, Anderson A, Pollock J, Zellner W, Schoelz J, Leisner SM. Hapiak M, et al. Among authors: agama k. Virus Res. 2008 Dec;138(1-2):119-29. doi: 10.1016/j.virusres.2008.09.002. Epub 2008 Oct 28. Virus Res. 2008. PMID: 18851998 Free PMC article.
Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents.
Zhang XR, Wang HW, Tang WL, Zhang Y, Yang H, Hu DX, Ravji A, Marchand C, Kiselev E, Ofori-Atta K, Agama K, Pommier Y, An LK. Zhang XR, et al. Among authors: agama k. J Med Chem. 2018 Nov 21;61(22):9908-9930. doi: 10.1021/acs.jmedchem.8b00639. Epub 2018 Oct 31. J Med Chem. 2018. PMID: 30336023 Free PMC article.
Synthesis and biological evaluation of the first dual tyrosyl-DNA phosphodiesterase I (Tdp1)-topoisomerase I (Top1) inhibitors.
Nguyen TX, Morrell A, Conda-Sheridan M, Marchand C, Agama K, Bermingham A, Bermingam A, Stephen AG, Chergui A, Naumova A, Fisher R, O'Keefe BR, Pommier Y, Cushman M. Nguyen TX, et al. Among authors: agama k. J Med Chem. 2012 May 10;55(9):4457-78. doi: 10.1021/jm300335n. Epub 2012 Apr 26. J Med Chem. 2012. PMID: 22536944 Free PMC article.
Synthesis and biological evaluation of indenoisoquinolines that inhibit both tyrosyl-DNA phosphodiesterase I (Tdp1) and topoisomerase I (Top1).
Conda-Sheridan M, Reddy PV, Morrell A, Cobb BT, Marchand C, Agama K, Chergui A, Renaud A, Stephen AG, Bindu LK, Pommier Y, Cushman M. Conda-Sheridan M, et al. Among authors: agama k. J Med Chem. 2013 Jan 10;56(1):182-200. doi: 10.1021/jm3014458. Epub 2012 Dec 21. J Med Chem. 2013. PMID: 23259865 Free PMC article.
84 results