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Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine.
Sadri-Vakili G, Kumaresan V, Schmidt HD, Famous KR, Chawla P, Vassoler FM, Overland RP, Xia E, Bass CE, Terwilliger EF, Pierce RC, Cha JH. Sadri-Vakili G, et al. Among authors: cha jh. J Neurosci. 2010 Sep 1;30(35):11735-44. doi: 10.1523/JNEUROSCI.2328-10.2010. J Neurosci. 2010. PMID: 20810894 Free PMC article.
Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation at BDNF exon I-containing promoters.
Schmidt HD, Sangrey GR, Darnell SB, Schassburger RL, Cha JH, Pierce RC, Sadri-Vakili G. Schmidt HD, et al. Among authors: cha jh. J Neurochem. 2012 Jan;120(2):202-9. doi: 10.1111/j.1471-4159.2011.07571.x. Epub 2011 Nov 28. J Neurochem. 2012. PMID: 22043863 Free PMC article.
669 results