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Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines.
Saurwein-Teissl M, Lung TL, Marx F, Gschösser C, Asch E, Blasko I, Parson W, Böck G, Schönitzer D, Trannoy E, Grubeck-Loebenstein B. Saurwein-Teissl M, et al. Among authors: parson w. J Immunol. 2002 Jun 1;168(11):5893-9. doi: 10.4049/jimmunol.168.11.5893. J Immunol. 2002. PMID: 12023394
CD25-expressing CD8+ T cells are potent memory cells in old age.
Herndler-Brandstetter D, Schwaiger S, Veel E, Fehrer C, Cioca DP, Almanzar G, Keller M, Pfister G, Parson W, Würzner R, Schönitzer D, Henson SM, Aspinall R, Lepperdinger G, Grubeck-Loebenstein B. Herndler-Brandstetter D, et al. Among authors: parson w. J Immunol. 2005 Aug 1;175(3):1566-74. doi: 10.4049/jimmunol.175.3.1566. J Immunol. 2005. PMID: 16034095
Naive T cells in the elderly: are they still there?
Pfister G, Weiskopf D, Lazuardi L, Kovaiou RD, Cioca DP, Keller M, Lorbeg B, Parson W, Grubeck-Loebenstein B. Pfister G, et al. Among authors: parson w. Ann N Y Acad Sci. 2006 May;1067:152-7. doi: 10.1196/annals.1354.018. Ann N Y Acad Sci. 2006. PMID: 16803980
Oxidative stress can alter the antigenicity of immunodominant peptides.
Weiskopf D, Schwanninger A, Weinberger B, Almanzar G, Parson W, Buus S, Lindner H, Grubeck-Loebenstein B. Weiskopf D, et al. Among authors: parson w. J Leukoc Biol. 2010 Jan;87(1):165-72. doi: 10.1189/jlb.0209065. Epub 2009 Oct 2. J Leukoc Biol. 2010. PMID: 19801502
536 results