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CRISPR screens identify tumor-promoting genes conferring melanoma cell plasticity and resistance.
Gautron A, Bachelot L, Aubry M, Leclerc D, Quéméner AM, Corre S, Rambow F, Paris A, Tardif N, Leclair HM, Marin-Bejar O, Coulouarn C, Marine JC, Galibert MD, Gilot D. Gautron A, et al. Among authors: leclair hm. EMBO Mol Med. 2021 May 7;13(5):e13466. doi: 10.15252/emmm.202013466. Epub 2021 Mar 16. EMBO Mol Med. 2021. PMID: 33724679 Free PMC article.
Treatment With Mycophenolate and Cyclophosphamide Leads to Clinically Meaningful Improvements in Patient-Reported Outcomes in Scleroderma Lung Disease: Results of Scleroderma Lung Study II.
Volkmann ER, Tashkin DP, LeClair H, Roth MD, Kim G, Goldin J, Clements PJ, Furst DE, Khanna D. Volkmann ER, et al. Among authors: leclair h. ACR Open Rheumatol. 2020 Jun;2(6):362-370. doi: 10.1002/acr2.11125. Epub 2020 May 20. ACR Open Rheumatol. 2020. PMID: 32432411 Free PMC article.
Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma.
Corre S, Tardif N, Mouchet N, Leclair HM, Boussemart L, Gautron A, Bachelot L, Perrot A, Soshilov A, Rogiers A, Rambow F, Dumontet E, Tarte K, Bessede A, Guillemin GJ, Marine JC, Denison MS, Gilot D, Galibert MD. Corre S, et al. Among authors: leclair hm. Nat Commun. 2018 Nov 14;9(1):4775. doi: 10.1038/s41467-018-06951-2. Nat Commun. 2018. PMID: 30429474 Free PMC article.
Pharmacological targeting of apelin impairs glioblastoma growth.
Harford-Wright E, Andre-Gregoire G, Jacobs KA, Treps L, Le Gonidec S, Leclair HM, Gonzalez-Diest S, Roux Q, Guillonneau F, Loussouarn D, Oliver L, Vallette FM, Foufelle F, Valet P, Davenport AP, Glen RC, Bidere N, Gavard J. Harford-Wright E, et al. Among authors: leclair hm. Brain. 2017 Nov 1;140(11):2939-2954. doi: 10.1093/brain/awx253. Brain. 2017. PMID: 29053791 Free PMC article.
The E3 ubiquitin ligase MARCH3 controls the endothelial barrier.
Leclair HM, André-Grégoire G, Treps L, Azzi S, Bidère N, Gavard J. Leclair HM, et al. FEBS Lett. 2016 Oct;590(20):3660-3668. doi: 10.1002/1873-3468.12417. Epub 2016 Sep 26. FEBS Lett. 2016. PMID: 27616439 Free PMC article.
24 results