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Discovery of a ligand that compensates for decreased endogenous agonist potency of melanocortin-4 receptor polymorphisms identified in obese humans.
Haskell-Luevano C, Xiang Z, Wilczynski AM, Haskell KR, Andreasen AM, Litherland SA, Millard WJ, Pogozheva ID, Mosberg HI, Sorenson NB. Haskell-Luevano C, et al. Among authors: litherland sa. Adv Exp Med Biol. 2009;611:509-10. doi: 10.1007/978-0-387-73657-0_221. Adv Exp Med Biol. 2009. PMID: 19400288 No abstract available.
Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R.
Ericson MD, Haslach EM, Schnell SM, Freeman KT, Xiang ZM, Portillo FP, Speth R, Litherland SA, Haskell-Luevano C. Ericson MD, et al. Among authors: litherland sa. ACS Chem Neurosci. 2021 Feb 3;12(3):542-556. doi: 10.1021/acschemneuro.0c00755. Epub 2021 Jan 20. ACS Chem Neurosci. 2021. PMID: 33470098 Free PMC article.
Csf2 and Ptgs2 Epigenetic Dysregulation in Diabetes-prone Bicongenic B6.NODC11bxC1tb Mice.
Garrigan E, Belkin NS, Seydel F, Han Z, Carter J, McDuffie M, Morel L, Peck AB, Clare-Salzler MJ, Atkinson M, Wasserfall C, Davoodi-Semiromi A, Shi JD, Haskell-Luevano C, Yang LJ, Alexander JJ, Cdebaca A, Piliant T, Riggs C, Amick M, Litherland SA. Garrigan E, et al. Among authors: litherland sa. Genet Epigenet. 2015 Oct 11;7:5-17. doi: 10.4137/GEG.S29696. eCollection 2015. Genet Epigenet. 2015. PMID: 26512207 Free PMC article.
37 results