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Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro.
Butler TJ, Estep KN, Sommers JA, Maul RW, Moore AZ, Bandinelli S, Cucca F, Tuke MA, Wood AR, Bharti SK, Bogenhagen DF, Yakubovskaya E, Garcia-Diaz M, Guilliam TA, Byrd AK, Raney KD, Doherty AJ, Ferrucci L, Schlessinger D, Ding J, Brosh RM. Butler TJ, et al. Among authors: yakubovskaya e. Hum Mol Genet. 2020 May 28;29(8):1292-1309. doi: 10.1093/hmg/ddaa043. Hum Mol Genet. 2020. PMID: 32191790 Free PMC article.
Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING.
Khan I, Crouch JD, Bharti SK, Sommers JA, Carney SM, Yakubovskaya E, Garcia-Diaz M, Trakselis MA, Brosh RM Jr. Khan I, et al. Among authors: yakubovskaya e. J Biol Chem. 2016 Jul 1;291(27):14324-14339. doi: 10.1074/jbc.M115.712026. Epub 2016 May 11. J Biol Chem. 2016. PMID: 27226550 Free PMC article.
Organization of the human mitochondrial transcription initiation complex.
Yakubovskaya E, Guja KE, Eng ET, Choi WS, Mejia E, Beglov D, Lukin M, Kozakov D, Garcia-Diaz M. Yakubovskaya E, et al. Nucleic Acids Res. 2014 Apr;42(6):4100-12. doi: 10.1093/nar/gkt1360. Epub 2014 Jan 9. Nucleic Acids Res. 2014. PMID: 24413562 Free PMC article.
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