Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.
Chan J, Yamazaki H, Ishiyama N, Seo MD, Mal TK, Michikawa T, Mikoshiba K, Ikura M.
Chan J, et al.
J Biol Chem. 2010 Nov 12;285(46):36092-9. doi: 10.1074/jbc.M110.140160. Epub 2010 Sep 15.
J Biol Chem. 2010.
PMID: 20843799
Free PMC article.
Our NMR and biochemical studies showed that three spatially clustered residues (Glu-20, Tyr-167, and Ser-217 in IP(3)R1 and Glu-19, Trp-168, and Ser-218 in IP(3)R3) within the N-terminal suppressor domains of IP(3)R1(SUP) and IP(3)R3(SUP) interact directly with their respective C …
Our NMR and biochemical studies showed that three spatially clustered residues (Glu-20, Tyr-167, and Ser-217 in IP(3)R1 and Glu-19, Trp-168, …