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Chromosome 8q23.3 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome.
Wijnen JT, Brohet RM, van Eijk R, Jagmohan-Changur S, Middeldorp A, Tops CM, van Puijenbroek M, Ausems MG, Gómez García E, Hes FJ, Hoogerbrugge N, Menko FH, van Os TA, Sijmons RH, Verhoef S, Wagner A, Nagengast FM, Kleibeuker JH, Devilee P, Morreau H, Goldgar D, Tomlinson IP, Houlston RS, van Wezel T, Vasen HF. Wijnen JT, et al. Among authors: sijmons rh. Gastroenterology. 2009 Jan;136(1):131-7. doi: 10.1053/j.gastro.2008.09.033. Epub 2008 Sep 25. Gastroenterology. 2009. PMID: 19010329
Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis.
Hes FJ, Ruano D, Nieuwenhuis M, Tops CM, Schrumpf M, Nielsen M, Huijts PE, Wijnen JT, Wagner A, Gómez García EB, Sijmons RH, Menko FH, Letteboer TG, Hoogerbrugge N, Harryvan J, Kampman E, Morreau H, Vasen HF, van Wezel T. Hes FJ, et al. Among authors: sijmons rh. J Med Genet. 2014 Jan;51(1):55-60. doi: 10.1136/jmedgenet-2013-102000. Epub 2013 Nov 19. J Med Genet. 2014. PMID: 24253443 Free PMC article.
Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia.
Schubert SA, Ruano D, Elsayed FA, Boot A, Crobach S, Sarasqueta AF, Wolffenbuttel B, van der Klauw MM, Oosting J, Tops CM, van Eijk R, Vasen HF, Vossen RH, Nielsen M, Castellví-Bel S, Ruiz-Ponte C, Tomlinson I, Dunlop MG, Vodicka P, Wijnen JT, Hes FJ, Morreau H, de Miranda NF, Sijmons RH, van Wezel T. Schubert SA, et al. Among authors: sijmons rh. Br J Cancer. 2017 Sep 5;117(6):1215-1223. doi: 10.1038/bjc.2017.240. Epub 2017 Jul 25. Br J Cancer. 2017. PMID: 28742792 Free PMC article.
Colorectal cancer risk variants at 8q23.3 and 11q23.1 are associated with disease phenotype in APC mutation carriers.
Ghorbanoghli Z, Nieuwenhuis MH, Houwing-Duistermaat JJ, Jagmohan-Changur S, Hes FJ, Tops CM, Wagner A, Aalfs CM, Verhoef S, Gómez García EB, Sijmons RH, Menko FH, Letteboer TG, Hoogerbrugge N, van Wezel T, Vasen HF, Wijnen JT. Ghorbanoghli Z, et al. Among authors: sijmons rh. Fam Cancer. 2016 Oct;15(4):563-70. doi: 10.1007/s10689-016-9877-5. Fam Cancer. 2016. PMID: 26880076 Free PMC article.
Accuracy of Hereditary Diffuse Gastric Cancer Testing Criteria and Outcomes in Patients With a Germline Mutation in CDH1.
van der Post RS, Vogelaar IP, Manders P, van der Kolk LE, Cats A, van Hest LP, Sijmons R, Aalfs CM, Ausems MG, Gómez García EB, Wagner A, Hes FJ, Arts N, Mensenkamp AR, van Krieken JH, Hoogerbrugge N, Ligtenberg MJ. van der Post RS, et al. Gastroenterology. 2015 Oct;149(4):897-906.e19. doi: 10.1053/j.gastro.2015.06.003. Epub 2015 Jun 11. Gastroenterology. 2015. PMID: 26072394
No association between two MLH3 variants (S845G and P844L)and colorectal cancer risk.
de Jong MM, Hofstra RM, Kooi KA, Westra JL, Berends MJ, Wu Y, Hollema H, van der Sluis T, van der Graaf WT, de Vries EG, Schaapveld M, Sijmons RH, te Meerman GJ, Kleibeuker JH. de Jong MM, et al. Among authors: sijmons rh. Cancer Genet Cytogenet. 2004 Jul 1;152(1):70-1. doi: 10.1016/j.cancergencyto.2003.10.008. Cancer Genet Cytogenet. 2004. PMID: 15193445
MUTYH and the mismatch repair system: partners in crime?
Niessen RC, Sijmons RH, Ou J, Olthof SG, Osinga J, Ligtenberg MJ, Hogervorst FB, Weiss MM, Tops CM, Hes FJ, de Bock GH, Buys CH, Kleibeuker JH, Hofstra RM. Niessen RC, et al. Among authors: sijmons rh. Hum Genet. 2006 Mar;119(1-2):206-11. doi: 10.1007/s00439-005-0118-5. Epub 2006 Jan 12. Hum Genet. 2006. PMID: 16408224
PMS2 involvement in patients suspected of Lynch syndrome.
Niessen RC, Kleibeuker JH, Westers H, Jager PO, Rozeveld D, Bos KK, Boersma-van Ek W, Hollema H, Sijmons RH, Hofstra RM. Niessen RC, et al. Among authors: sijmons rh. Genes Chromosomes Cancer. 2009 Apr;48(4):322-9. doi: 10.1002/gcc.20642. Genes Chromosomes Cancer. 2009. PMID: 19132747
192 results