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Phosphatidylinositol 3-kinase hyperactivation results in lapatinib resistance that is reversed by the mTOR/phosphatidylinositol 3-kinase inhibitor NVP-BEZ235.
Eichhorn PJ, Gili M, Scaltriti M, Serra V, Guzman M, Nijkamp W, Beijersbergen RL, Valero V, Seoane J, Bernards R, Baselga J. Eichhorn PJ, et al. Among authors: bernards r. Cancer Res. 2008 Nov 15;68(22):9221-30. doi: 10.1158/0008-5472.CAN-08-1740. Cancer Res. 2008. PMID: 19010894 Free PMC article.
Functional analysis of Burkitt's lymphoma mutant c-Myc proteins.
Smith-Sørensen B, Hijmans EM, Beijersbergen RL, Bernards R. Smith-Sørensen B, et al. Among authors: bernards r. J Biol Chem. 1996 Mar 8;271(10):5513-8. doi: 10.1074/jbc.271.10.5513. J Biol Chem. 1996. PMID: 8621409 Free article.
A large-scale RNAi screen in human cells identifies new components of the p53 pathway.
Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, Heimerikx M, Kerkhoven RM, Madiredjo M, Nijkamp W, Weigelt B, Agami R, Ge W, Cavet G, Linsley PS, Beijersbergen RL, Bernards R. Berns K, et al. Among authors: bernards r. Nature. 2004 Mar 25;428(6981):431-7. doi: 10.1038/nature02371. Nature. 2004. PMID: 15042092
Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells.
Nicke B, Bastien J, Khanna SJ, Warne PH, Cowling V, Cook SJ, Peters G, Delpuech O, Schulze A, Berns K, Mullenders J, Beijersbergen RL, Bernards R, Ganesan TS, Downward J, Hancock DC. Nicke B, et al. Among authors: bernards r. Mol Cell. 2005 Dec 9;20(5):673-85. doi: 10.1016/j.molcel.2005.10.038. Mol Cell. 2005. PMID: 16337592 Free article.
331 results