Clarke AR - Search Results

1

Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation.

Marsh V, Winton DJ, Williams GT, Dubois N, Trumpp A, Sansom OJ, Clarke AR. Marsh V, et al. Among authors: clarke ar. Nat Genet. 2008 Dec;40(12):1436-44. doi: 10.1038/ng.256. Epub 2008 Nov 16. Nat Genet. 2008. PMID: 19011632

2

Deficiency of Mbd2 suppresses intestinal tumorigenesis.

Sansom OJ, Berger J, Bishop SM, Hendrich B, Bird A, Clarke AR. Sansom OJ, et al. Among authors: clarke ar. Nat Genet. 2003 Jun;34(2):145-7. doi: 10.1038/ng1155. Nat Genet. 2003. PMID: 12730693

3

PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine.

Reed KR, Sansom OJ, Hayes AJ, Gescher AJ, Winton DJ, Peters JM, Clarke AR. Reed KR, et al. Among authors: clarke ar. Oncogene. 2004 Nov 25;23(55):8992-6. doi: 10.1038/sj.onc.1208143. Oncogene. 2004. PMID: 15480419

4

Myc deletion rescues Apc deficiency in the small intestine.

Sansom OJ, Meniel VS, Muncan V, Phesse TJ, Wilkins JA, Reed KR, Vass JK, Athineos D, Clevers H, Clarke AR. Sansom OJ, et al. Among authors: clarke ar. Nature. 2007 Apr 5;446(7136):676-9. doi: 10.1038/nature05674. Epub 2007 Mar 21. Nature. 2007. PMID: 17377531

5

A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine.

Reed KR, Meniel VS, Marsh V, Cole A, Sansom OJ, Clarke AR. Reed KR, et al. Among authors: clarke ar. BMC Cancer. 2008 Jun 5;8:162. doi: 10.1186/1471-2407-8-162. BMC Cancer. 2008. PMID: 18533991 Free PMC article.

6

B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver.

Reed KR, Athineos D, Meniel VS, Wilkins JA, Ridgway RA, Burke ZD, Muncan V, Clarke AR, Sansom OJ. Reed KR, et al. Among authors: clarke ar. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18919-23. doi: 10.1073/pnas.0805778105. Epub 2008 Nov 24. Proc Natl Acad Sci U S A. 2008. PMID: 19033191 Free PMC article.

7

PTEN loss and KRAS activation cooperate in murine biliary tract malignancies.

Marsh V, Davies EJ, Williams GT, Clarke AR. Marsh V, et al. Among authors: clarke ar. J Pathol. 2013 Jun;230(2):165-73. doi: 10.1002/path.4189. J Pathol. 2013. PMID: 23483557

8

Intestinal homeostasis and neoplasia studied using conditional transgenesis.

Marsh V, Clarke A. Marsh V, et al. Expert Rev Anticancer Ther. 2007 Apr;7(4):519-31. doi: 10.1586/14737140.7.4.519. Expert Rev Anticancer Ther. 2007. PMID: 17428172 Review.

9

Analyzing tumor suppressor activities in the murine small intestine.

Clarke AR, Sansom OJ. Clarke AR, et al. Oncol Res. 2003;13(6-10):333-7. doi: 10.3727/096504003108748537. Oncol Res. 2003. PMID: 12725522 Review.

10

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.

Sansom OJ, Reed KR, Hayes AJ, Ireland H, Brinkmann H, Newton IP, Batlle E, Simon-Assmann P, Clevers H, Nathke IS, Clarke AR, Winton DJ. Sansom OJ, et al. Among authors: clarke ar. Genes Dev. 2004 Jun 15;18(12):1385-90. doi: 10.1101/gad.287404. Genes Dev. 2004. PMID: 15198980 Free PMC article.

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