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Asp-to-Asn substitution at the first position of the DxD TOPRIM motif of recombinant bacterial topoisomerase I is extremely lethal to E. coli.
J Mol Biol. 2009 Jan 16;385(2):558-67. doi: 10.1016/j.jmb.2008.10.073. Epub 2008 Nov 5.
J Mol Biol. 2009.
PMID: 19013470
Free PMC article.
Inhibition of Mg2+ binding and DNA religation by bacterial topoisomerase I via introduction of an additional positive charge into the active site region.
Sorokin EP, Cheng B, Rathi S, Aedo SJ, Abrenica MV, Tse-Dinh YC.
Sorokin EP, et al. Among authors: abrenica mv.
Nucleic Acids Res. 2008 Aug;36(14):4788-96. doi: 10.1093/nar/gkn460. Epub 2008 Jul 24.
Nucleic Acids Res. 2008.
PMID: 18653534
Free PMC article.
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The DNA relaxation activity and covalent complex accumulation of Mycobacterium tuberculosis topoisomerase I can be assayed in Escherichia coli: application for identification of potential FRET-dye labeling sites.
Narula G, Becker J, Cheng B, Dani N, Abrenica MV, Tse-Dinh YC.
Narula G, et al. Among authors: abrenica mv.
BMC Biochem. 2010 Sep 30;11:41. doi: 10.1186/1471-2091-11-41.
BMC Biochem. 2010.
PMID: 20920291
Free PMC article.
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Comparative study of mupirocin and sodium fucidate in the prophylaxis of exit-site infections in CAPD patients.
Danguilan RA, Evangelista LP, Abrenica MS, Rondilla SM.
Danguilan RA, et al. Among authors: abrenica ms.
Perit Dial Int. 2003 Nov-Dec;23(6):593-5.
Perit Dial Int. 2003.
PMID: 14703203
Clinical Trial.
No abstract available.
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