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STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk.
Abelson AK, Delgado-Vega AM, Kozyrev SV, Sánchez E, Velázquez-Cruz R, Eriksson N, Wojcik J, Linga Reddy MV, Lima G, D'Alfonso S, Migliaresi S, Baca V, Orozco L, Witte T, Ortego-Centeno N; AADEA group; Abderrahim H, Pons-Estel BA, Gutiérrez C, Suárez A, González-Escribano MF, Martin J, Alarcón-Riquelme ME. Abelson AK, et al. Ann Rheum Dis. 2009 Nov;68(11):1746-53. doi: 10.1136/ard.2008.097642. Epub 2008 Nov 19. Ann Rheum Dis. 2009. PMID: 19019891 Free PMC article.
No evidence of association between genetic variants of the PDCD1 ligands and SLE.
Abelson AK, Johansson CM, Kozyrev SV, Kristjansdottir H, Gunnarsson I, Svenungsson E, Jönsen A, Lima G, Scherbarth HR, Gamron S, Allievi A, Palatnik SA, Alvarellos A, Paira S, Graf C, Guillerón C, Catoggio LJ, Prigione C, Battagliotti CG, Berbotto GA, García MA, Perandones CE, Truedsson L, Steinsson K, Sturfelt G, Pons-Estel B; Argentinean Collaborative Group; Alarcón-Riquelme ME. Abelson AK, et al. Genes Immun. 2007 Jan;8(1):69-74. doi: 10.1038/sj.gene.6364360. Epub 2006 Nov 30. Genes Immun. 2007. PMID: 17136123
Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus.
Sreih A, Ezzeddine R, Leng L, LaChance A, Yu G, Mizue Y, Subrahmanyan L, Pons-Estel BA, Abelson AK, Gunnarsson I, Svenungsson E, Cavett J, Glenn S, Zhang L, Montgomery R, Perl A, Salmon J, Alarcón-Riquelme ME, Harley JB, Bucala R. Sreih A, et al. Among authors: abelson ak. Arthritis Rheum. 2011 Dec;63(12):3942-51. doi: 10.1002/art.30624. Arthritis Rheum. 2011. PMID: 22127710 Free PMC article.
Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans.
Liu K, Li QZ, Delgado-Vega AM, Abelson AK, Sánchez E, Kelly JA, Li L, Liu Y, Zhou J, Yan M, Ye Q, Liu S, Xie C, Zhou XJ, Chung SA, Pons-Estel B, Witte T, de Ramón E, Bae SC, Barizzone N, Sebastiani GD, Merrill JT, Gregersen PK, Gilkeson GG, Kimberly RP, Vyse TJ, Kim I, D'Alfonso S, Martin J, Harley JB, Criswell LA; Profile Study Group; Italian Collaborative Group; German Collaborative Group; Spanish Collaborative Group; Argentinian Collaborative Group; SLEGEN Consortium; Wakeland EK, Alarcón-Riquelme ME, Mohan C. Liu K, et al. Among authors: abelson ak. J Clin Invest. 2009 Apr;119(4):911-23. doi: 10.1172/JCI36728. J Clin Invest. 2009. PMID: 19307730 Free PMC article.
Study of functional variants of the BANK1 gene in rheumatoid arthritis.
Orozco G, Abelson AK, González-Gay MA, Balsa A, Pascual-Salcedo D, García A, Fernández-Gutierrez B, Petersson I, Pons-Estel B, Eimon A, Paira S, Scherbarth HR, Alarcón-Riquelme M, Martín J. Orozco G, et al. Among authors: abelson ak. Arthritis Rheum. 2009 Feb;60(2):372-9. doi: 10.1002/art.24244. Arthritis Rheum. 2009. PMID: 19180476 Free article.
Corrigendum: Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.
Kozyrev SV, Abelson AK, Wojcik J, Zaghlool A, Linga Reddy MP, Sanchez E, Gunnarsson I, Svenungsson E, Sturfelt G, Jönsen A, Truedsson L, Pons-Estel BA, Witte T, D'Alfonso S, Barrizzone N, Danieli MG, Gutierrez C, Suarez A, Junker P, Laustrup H, Francisca González-Escribano M, Martin J, Abderrahim H, Alarcón-Riquelme ME. Kozyrev SV, et al. Among authors: abelson ak. Nat Genet. 2008 Apr;40(4):484. doi: 10.1038/ng0408-484. Nat Genet. 2008. PMID: 18368128 No abstract available.
Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.
Kozyrev SV, Abelson AK, Wojcik J, Zaghlool A, Linga Reddy MV, Sanchez E, Gunnarsson I, Svenungsson E, Sturfelt G, Jönsen A, Truedsson L, Pons-Estel BA, Witte T, D'Alfonso S, Barizzone N, Danieli MG, Gutierrez C, Suarez A, Junker P, Laustrup H, González-Escribano MF, Martin J, Abderrahim H, Alarcón-Riquelme ME. Kozyrev SV, et al. Among authors: abelson ak. Nat Genet. 2008 Feb;40(2):211-6. doi: 10.1038/ng.79. Epub 2008 Jan 20. Nat Genet. 2008. PMID: 18204447
Association of a CD24 gene polymorphism with susceptibility to systemic lupus erythematosus.
Sánchez E, Abelson AK, Sabio JM, González-Gay MA, Ortego-Centeno N, Jiménez-Alonso J, de Ramón E, Sánchez-Román J, López-Nevot MA, Gunnarsson I, Svenungsson E, Sturfelt G, Truedsson L, Jönsen A, González-Escribano MF, Witte T; German Systemic Lupus Erythematosus Study Group; Alarcón-Riquelme ME, Martín J. Sánchez E, et al. Among authors: abelson ak. Arthritis Rheum. 2007 Sep;56(9):3080-6. doi: 10.1002/art.22871. Arthritis Rheum. 2007. PMID: 17763438 Free article.