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STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk.
Abelson AK, Delgado-Vega AM, Kozyrev SV, Sánchez E, Velázquez-Cruz R, Eriksson N, Wojcik J, Linga Reddy MV, Lima G, D'Alfonso S, Migliaresi S, Baca V, Orozco L, Witte T, Ortego-Centeno N; AADEA group; Abderrahim H, Pons-Estel BA, Gutiérrez C, Suárez A, González-Escribano MF, Martin J, Alarcón-Riquelme ME. Abelson AK, et al. Among authors: martin j. Ann Rheum Dis. 2009 Nov;68(11):1746-53. doi: 10.1136/ard.2008.097642. Epub 2008 Nov 19. Ann Rheum Dis. 2009. PMID: 19019891 Free PMC article.
Study of the role of functional variants of SLC22A4, RUNX1 and SUMO4 in systemic lupus erythematosus.
Orozco G, Sánchez E, Gómez LM, González-Gay MA, López-Nevot MA, Torres B, Ortego-Centeno N, Jiménez-Alonso J, de Ramón E, Sánchez Román J, Anaya JM, Sturfelt G, Gunnarsson I, Svennungsson E, Alarcón-Riquelme M, González-Escribano MF, Martín J. Orozco G, et al. Among authors: martin j. Ann Rheum Dis. 2006 Jun;65(6):791-5. doi: 10.1136/ard.2005.044891. Epub 2005 Oct 25. Ann Rheum Dis. 2006. PMID: 16249223 Free PMC article.
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus.
Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, Bauer JW, Ortmann WA, Koeuth T, González Escribano MF; Argentine and Spanish Collaborative Groups; Pons-Estel B, Petri M, Daly M, Gregersen PK, Martín J, Altshuler D, Behrens TW, Alarcón-Riquelme ME. Graham RR, et al. Among authors: martin j. Nat Genet. 2006 May;38(5):550-5. doi: 10.1038/ng1782. Epub 2006 Apr 16. Nat Genet. 2006. PMID: 16642019
Interleukin 12 (IL12B), interleukin 12 receptor (IL12RB1) and interleukin 23 (IL23A) gene polymorphism in systemic lupus erythematosus.
Sánchez E, Morales S, Paco L, López-Nevot MA, Hidalgo C, Jiménez-Alonso J, Torres B, González-Gay MA, Callejas JL, Ortego-Centeno N, Sánchez-Roman J, González-Escribano MF, Martín J. Sánchez E, et al. Among authors: martin j. Rheumatology (Oxford). 2005 Sep;44(9):1136-9. doi: 10.1093/rheumatology/keh697. Epub 2005 Jun 7. Rheumatology (Oxford). 2005. PMID: 15941730
No primary association of MICA polymorphism with systemic lupus erythematosus.
Sánchez E, Torres B, Vilches JR, López-Nevot MA, Ortego-Centeno N, Jiménez-Alonso J, González-Gay MA, de Ramón E, Sánchez-Román J, Núñez-Roldán A, Martín J, González-Escribano MF. Sánchez E, et al. Among authors: martin j. Rheumatology (Oxford). 2006 Sep;45(9):1096-100. doi: 10.1093/rheumatology/kel058. Epub 2006 Mar 14. Rheumatology (Oxford). 2006. PMID: 16537577
Investigating the role of CD24 gene polymorphisms in rheumatoid arthritis.
Sánchez E, Fernández-Gutierrez B, González-Gay MA, Balsa A, García A, Rodríguez L, Pascual-Salcedo D, González-Escribano MF, Martin J. Sánchez E, et al. Among authors: martin j. Ann Rheum Dis. 2008 Aug;67(8):1197-8. doi: 10.1136/ard.2007.084475. Ann Rheum Dis. 2008. PMID: 18621973 No abstract available.
The interleukin 23 receptor gene does not confer risk to systemic sclerosis and is not associated with systemic sclerosis disease phenotype.
Rueda B, Broen J, Torres O, Simeon C, Ortego-Centeno N, Schrijvenaars MM, Vonk MC, Fonollosa V, van den Hoogen FH, Coenen MJ, Sanchez-Román J, Aguirre-Zamorano MA, García-Portales R, Pros A, Camps MT, Gonzalez-Gay MA, Martin J, Radstake TR. Rueda B, et al. Among authors: martin j. Ann Rheum Dis. 2009 Feb;68(2):253-6. doi: 10.1136/ard.2008.096719. Epub 2008 Aug 19. Ann Rheum Dis. 2009. PMID: 18713787
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