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STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk.
Abelson AK, Delgado-Vega AM, Kozyrev SV, Sánchez E, Velázquez-Cruz R, Eriksson N, Wojcik J, Linga Reddy MV, Lima G, D'Alfonso S, Migliaresi S, Baca V, Orozco L, Witte T, Ortego-Centeno N; AADEA group; Abderrahim H, Pons-Estel BA, Gutiérrez C, Suárez A, González-Escribano MF, Martin J, Alarcón-Riquelme ME. Abelson AK, et al. Ann Rheum Dis. 2009 Nov;68(11):1746-53. doi: 10.1136/ard.2008.097642. Epub 2008 Nov 19. Ann Rheum Dis. 2009. PMID: 19019891 Free PMC article.
Association of PDCD1 polymorphisms with childhood-onset systemic lupus erythematosus.
Velázquez-Cruz R, Orozco L, Espinosa-Rosales F, Carreño-Manjarrez R, Solís-Vallejo E, López-Lara ND, Ruiz-López IK, Rodríguez-Lozano AL, Estrada-Gil JK, Jiménez-Sánchez G, Baca V. Velázquez-Cruz R, et al. Eur J Hum Genet. 2007 Mar;15(3):336-41. doi: 10.1038/sj.ejhg.5201767. Epub 2007 Jan 17. Eur J Hum Genet. 2007. PMID: 17228327
Tumor necrosis factor-alpha is a common genetic risk factor for asthma, juvenile rheumatoid arthritis, and systemic lupus erythematosus in a Mexican pediatric population.
Jiménez-Morales S, Velázquez-Cruz R, Ramírez-Bello J, Bonilla-González E, Romero-Hidalgo S, Escamilla-Guerrero G, Cuevas F, Espinosa-Rosales F, Martínez-Aguilar NE, Gómez-Vera J, Baca V, Orozco L. Jiménez-Morales S, et al. Hum Immunol. 2009 Apr;70(4):251-6. doi: 10.1016/j.humimm.2009.01.027. Epub 2009 Feb 4. Hum Immunol. 2009. PMID: 19480843
108 results