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Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.
Bisgaard H, Bønnelykke K, Sleiman PM, Brasholt M, Chawes B, Kreiner-Møller E, Stage M, Kim C, Tavendale R, Baty F, Pipper CB, Palmer CN, Hakonarsson H. Bisgaard H, et al. Among authors: hakonarsson h. Am J Respir Crit Care Med. 2009 Feb 1;179(3):179-85. doi: 10.1164/rccm.200809-1436OC. Epub 2008 Nov 21. Am J Respir Crit Care Med. 2009. PMID: 19029000
VEGFA variants are associated with pre-school lung function, but not neonatal lung function.
Kreiner-Møller E, Chawes BL, Vissing NH, Koppelman GH, Postma DS, Madsen JS, Olsen DA, Baty F, Vonk JM, Kerkhof M, Sleiman P, Hakonarsson H, Mortensen LJ, Poorisrisak P, Bisgaard H, Bønnelykke K. Kreiner-Møller E, et al. Among authors: hakonarsson h. Clin Exp Allergy. 2013 Nov;43(11):1236-45. doi: 10.1111/cea.12188. Clin Exp Allergy. 2013. PMID: 24152156
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.
Bønnelykke K, Matheson MC, Pers TH, Granell R, Strachan DP, Alves AC, Linneberg A, Curtin JA, Warrington NM, Standl M, Kerkhof M, Jonsdottir I, Bukvic BK, Kaakinen M, Sleimann P, Thorleifsson G, Thorsteinsdottir U, Schramm K, Baltic S, Kreiner-Møller E, Simpson A, St Pourcain B, Coin L, Hui J, Walters EH, Tiesler CMT, Duffy DL, Jones G; AAGC; Ring SM, McArdle WL, Price L, Robertson CF, Pekkanen J, Tang CS, Thiering E, Montgomery GW, Hartikainen AL, Dharmage SC, Husemoen LL, Herder C, Kemp JP, Elliot P, James A, Waldenberger M, Abramson MJ, Fairfax BP, Knight JC, Gupta R, Thompson PJ, Holt P, Sly P, Hirschhorn JN, Blekic M, Weidinger S, Hakonarsson H, Stefansson K, Heinrich J, Postma DS, Custovic A, Pennell CE, Jarvelin MR, Koppelman GH, Timpson N, Ferreira MA, Bisgaard H, Henderson AJ. Bønnelykke K, et al. Among authors: hakonarsson h. Nat Genet. 2013 Aug;45(8):902-906. doi: 10.1038/ng.2694. Epub 2013 Jun 30. Nat Genet. 2013. PMID: 23817571 Free PMC article.