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701 results

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cSSMD: assessing collective activity for addressing off-target effects in genome-scale RNA interference screens.
Zhang XD, Santini F, Lacson R, Marine SD, Wu Q, Benetti L, Yang R, McCampbell A, Berger JP, Toolan DM, Stec EM, Holder DJ, Soper KA, Heyse JF, Ferrer M. Zhang XD, et al. Among authors: santini f. Bioinformatics. 2011 Oct 15;27(20):2775-81. doi: 10.1093/bioinformatics/btr474. Epub 2011 Aug 16. Bioinformatics. 2011. PMID: 21846737 Free PMC article.
Multiplexed assays by high-content imaging for assessment of GPCR activity.
Ross DA, Lee S, Reiser V, Xue J, Alves K, Vaidya S, Kreamer A, Mull R, Hudak E, Hare T, Detmers PA, Lingham R, Ferrer M, Strulovici B, Santini F. Ross DA, et al. Among authors: santini f. J Biomol Screen. 2008 Jul;13(6):449-55. doi: 10.1177/1087057108317685. Epub 2008 Jun 2. J Biomol Screen. 2008. PMID: 18519922
A multiplexed siRNA screening strategy to identify genes in the PARP pathway.
Stec E, Locco L, Szymanski S, Bartz SR, Toniatti C, Needham RH, Palmieri A, Carleton M, Cleary MA, Jackson AL, Linsley PS, Strulovici B, Ferrer M, Santini F. Stec E, et al. Among authors: santini f. J Biomol Screen. 2012 Dec;17(10):1316-28. doi: 10.1177/1087057112453071. Epub 2012 Jul 10. J Biomol Screen. 2012. PMID: 22786893
Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions.
Bartz SR, Zhang Z, Burchard J, Imakura M, Martin M, Palmieri A, Needham R, Guo J, Gordon M, Chung N, Warrener P, Jackson AL, Carleton M, Oatley M, Locco L, Santini F, Smith T, Kunapuli P, Ferrer M, Strulovici B, Friend SH, Linsley PS. Bartz SR, et al. Among authors: santini f. Mol Cell Biol. 2006 Dec;26(24):9377-86. doi: 10.1128/MCB.01229-06. Epub 2006 Sep 25. Mol Cell Biol. 2006. PMID: 17000754 Free PMC article.
Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption.
Zhao WQ, Santini F, Breese R, Ross D, Zhang XD, Stone DJ, Ferrer M, Townsend M, Wolfe AL, Seager MA, Kinney GG, Shughrue PJ, Ray WJ. Zhao WQ, et al. Among authors: santini f. J Biol Chem. 2010 Mar 5;285(10):7619-32. doi: 10.1074/jbc.M109.057182. Epub 2009 Dec 23. J Biol Chem. 2010. PMID: 20032460 Free PMC article.
701 results