Citro ML - Search Results

1

Aryl bis(diazeniumdiolates): potent inducers of S-glutathionylation of cellular proteins and their in vitro antiproliferative activities.

Andrei D, Maciag AE, Chakrapani H, Citro ML, Keefer LK, Saavedra JE. Andrei D, et al. Among authors: citro ml. J Med Chem. 2008 Dec 25;51(24):7944-52. doi: 10.1021/jm800831y. J Med Chem. 2008. PMID: 19053760 Free PMC article.

2

Carbon-bound diazeniumdiolates from the reaction of nitric oxide with amidines.

Hrabie JA, Citro ML, Chmurny GN, Keefer LK. Hrabie JA, et al. Among authors: citro ml. J Org Chem. 2005 Sep 16;70(19):7647-53. doi: 10.1021/jo050921y. J Org Chem. 2005. PMID: 16149795

3

PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.

Saavedra JE, Srinivasan A, Buzard GS, Davies KM, Waterhouse DJ, Inami K, Wilde TC, Citro ML, Cuellar M, Deschamps JR, Parrish D, Shami PJ, Findlay VJ, Townsend DM, Tew KD, Singh S, Jia L, Ji X, Keefer LK. Saavedra JE, et al. Among authors: citro ml. J Med Chem. 2006 Feb 9;49(3):1157-64. doi: 10.1021/jm050700k. J Med Chem. 2006. PMID: 16451080 Free PMC article.

4

O2-acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO-NSAIDs): synthesis, nitric oxide release, and biological evaluation studies.

Velázquez CA, Praveen Rao PN, Citro ML, Keefer LK, Knaus EE. Velázquez CA, et al. Among authors: citro ml. Bioorg Med Chem. 2007 Jul 15;15(14):4767-74. doi: 10.1016/j.bmc.2007.05.009. Epub 2007 May 6. Bioorg Med Chem. 2007. PMID: 17509888 Free PMC article.

5

Nitric oxide prodrugs: diazeniumdiolate anions of hindered secondary amines.

Chakrapani H, Showalter BM, Citro ML, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: citro ml. Org Lett. 2007 Oct 25;9(22):4551-4. doi: 10.1021/ol7019636. Epub 2007 Oct 5. Org Lett. 2007. PMID: 17918856

6

Synthesis, nitric oxide release, and anti-leukemic activity of glutathione-activated nitric oxide prodrugs: Structural analogues of PABA/NO, an anti-cancer lead compound.

Chakrapani H, Wilde TC, Citro ML, Goodblatt MM, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: citro ml. Bioorg Med Chem. 2008 Mar 1;16(5):2657-64. doi: 10.1016/j.bmc.2007.11.035. Epub 2007 Nov 17. Bioorg Med Chem. 2008. PMID: 18060792 Free PMC article.

7

Second-generation aspirin and indomethacin prodrugs possessing an O(2)-(acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate nitric oxide donor moiety: design, synthesis, biological evaluation, and nitric oxide release studies.

Velázquez CA, Chen QH, Citro ML, Keefer LK, Knaus EE. Velázquez CA, et al. Among authors: citro ml. J Med Chem. 2008 Mar 27;51(6):1954-61. doi: 10.1021/jm701450q. Epub 2008 Feb 29. J Med Chem. 2008. PMID: 18314945

8

Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity.

Valdez CA, Saavedra JE, Showalter BM, Davies KM, Wilde TC, Citro ML, Barchi JJ Jr, Deschamps JR, Parrish D, El-Gayar S, Schleicher U, Bogdan C, Keefer LK. Valdez CA, et al. Among authors: citro ml. J Med Chem. 2008 Jul 10;51(13):3961-70. doi: 10.1021/jm8000482. Epub 2008 Jun 6. J Med Chem. 2008. PMID: 18533711 Free PMC article.

9

Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs.

Chakrapani H, Kalathur RC, Maciag AE, Citro ML, Ji X, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: citro ml. Bioorg Med Chem. 2008 Nov 15;16(22):9764-71. doi: 10.1016/j.bmc.2008.09.063. Epub 2008 Sep 30. Bioorg Med Chem. 2008. PMID: 18930407 Free PMC article.

10

Cell-permeable esters of diazeniumdiolate-based nitric oxide prodrugs.

Chakrapani H, Maciag AE, Citro ML, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: citro ml. Org Lett. 2008 Nov 20;10(22):5155-8. doi: 10.1021/ol8020989. Epub 2008 Oct 29. Org Lett. 2008. PMID: 18956868 Free PMC article.

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