Keefer LK - Search Results

1

Aryl bis(diazeniumdiolates): potent inducers of S-glutathionylation of cellular proteins and their in vitro antiproliferative activities.

Andrei D, Maciag AE, Chakrapani H, Citro ML, Keefer LK, Saavedra JE. Andrei D, et al. Among authors: keefer lk. J Med Chem. 2008 Dec 25;51(24):7944-52. doi: 10.1021/jm800831y. J Med Chem. 2008. PMID: 19053760 Free PMC article.

2

Preparation and reactivity of O2-sulfonated diazeniumdiolates.

D'Sa RA, Wang Y, Ruane PH, Showalter BM, Saavedra JE, Davies KM, Citro ML, Booth MN, Keefer LK, Toscano JP. D'Sa RA, et al. Among authors: keefer lk. J Org Chem. 2003 Jan 24;68(2):656-7. doi: 10.1021/jo026656n. J Org Chem. 2003. PMID: 12530906

3

Carbon-bound diazeniumdiolates from the reaction of nitric oxide with amidines.

Hrabie JA, Citro ML, Chmurny GN, Keefer LK. Hrabie JA, et al. Among authors: keefer lk. J Org Chem. 2005 Sep 16;70(19):7647-53. doi: 10.1021/jo050921y. J Org Chem. 2005. PMID: 16149795

4

PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.

Saavedra JE, Srinivasan A, Buzard GS, Davies KM, Waterhouse DJ, Inami K, Wilde TC, Citro ML, Cuellar M, Deschamps JR, Parrish D, Shami PJ, Findlay VJ, Townsend DM, Tew KD, Singh S, Jia L, Ji X, Keefer LK. Saavedra JE, et al. Among authors: keefer lk. J Med Chem. 2006 Feb 9;49(3):1157-64. doi: 10.1021/jm050700k. J Med Chem. 2006. PMID: 16451080 Free PMC article.

5

O2-acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO-NSAIDs): synthesis, nitric oxide release, and biological evaluation studies.

Velázquez CA, Praveen Rao PN, Citro ML, Keefer LK, Knaus EE. Velázquez CA, et al. Among authors: keefer lk. Bioorg Med Chem. 2007 Jul 15;15(14):4767-74. doi: 10.1016/j.bmc.2007.05.009. Epub 2007 May 6. Bioorg Med Chem. 2007. PMID: 17509888 Free PMC article.

6

V-PROLI/NO, a prodrug of the nitric oxide donor, PROLI/NO.

Chakrapani H, Showalter BM, Kong L, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: keefer lk. Org Lett. 2007 Aug 16;9(17):3409-12. doi: 10.1021/ol701419a. Epub 2007 Jul 20. Org Lett. 2007. PMID: 17658755

7

Nitric oxide prodrugs: diazeniumdiolate anions of hindered secondary amines.

Chakrapani H, Showalter BM, Citro ML, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: keefer lk. Org Lett. 2007 Oct 25;9(22):4551-4. doi: 10.1021/ol7019636. Epub 2007 Oct 5. Org Lett. 2007. PMID: 17918856

8

Synthesis, nitric oxide release, and anti-leukemic activity of glutathione-activated nitric oxide prodrugs: Structural analogues of PABA/NO, an anti-cancer lead compound.

Chakrapani H, Wilde TC, Citro ML, Goodblatt MM, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: keefer lk. Bioorg Med Chem. 2008 Mar 1;16(5):2657-64. doi: 10.1016/j.bmc.2007.11.035. Epub 2007 Nov 17. Bioorg Med Chem. 2008. PMID: 18060792 Free PMC article.

9

Synthesis and in vitro anti-leukemic activity of structural analogues of JS-K, an anti-cancer lead compound.

Chakrapani H, Goodblatt MM, Udupi V, Malaviya S, Shami PJ, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: keefer lk. Bioorg Med Chem Lett. 2008 Feb 1;18(3):950-3. doi: 10.1016/j.bmcl.2007.12.044. Epub 2008 Jan 4. Bioorg Med Chem Lett. 2008. PMID: 18178089 Free PMC article.

10

Second-generation aspirin and indomethacin prodrugs possessing an O(2)-(acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate nitric oxide donor moiety: design, synthesis, biological evaluation, and nitric oxide release studies.

Velázquez CA, Chen QH, Citro ML, Keefer LK, Knaus EE. Velázquez CA, et al. Among authors: keefer lk. J Med Chem. 2008 Mar 27;51(6):1954-61. doi: 10.1021/jm701450q. Epub 2008 Feb 29. J Med Chem. 2008. PMID: 18314945

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

245 results

Search Page