Exploring the scope of the 29G12 antibody catalyzed 1,3-dipolar cycloaddition reaction.
Toker JD, Tremblay MR, Yli-Kauhaluoma J, Wentworth AD, Zhou B, Wentworth P Jr, Janda KD.
Toker JD, et al.
J Org Chem. 2005 Sep 30;70(20):7810-5. doi: 10.1021/jo050410b.
J Org Chem. 2005.
PMID: 16277300
[Chemical reaction: See text] 29G12 is a murine monoclonal antibody programmed to catalyze the regio- and enantioselective 1,3-dipolar cycloaddition reaction between 4-acetamidobenzonitrile N-oxide 1a and N,N-dimethylacrylamide 2a (Toker, J. D.; Wentworth, P., Jr.; Hu, Y.; Houk, …
[Chemical reaction: See text] 29G12 is a murine monoclonal antibody programmed to catalyze the regio- and enantioselective 1,3-dipolar cyclo …