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Singleton deletions throughout the genome increase risk of bipolar disorder.
Zhang D, Cheng L, Qian Y, Alliey-Rodriguez N, Kelsoe JR, Greenwood T, Nievergelt C, Barrett TB, McKinney R, Schork N, Smith EN, Bloss C, Nurnberger J, Edenberg HJ, Foroud T, Sheftner W, Lawson WB, Nwulia EA, Hipolito M, Coryell W, Rice J, Byerley W, McMahon F, Schulze TG, Berrettini W, Potash JB, Belmonte PL, Zandi PP, McInnis MG, Zöllner S, Craig D, Szelinger S, Koller D, Christian SL, Liu C, Gershon ES. Zhang D, et al. Among authors: cheng l. Mol Psychiatry. 2009 Apr;14(4):376-80. doi: 10.1038/mp.2008.144. Epub 2008 Dec 30. Mol Psychiatry. 2009. PMID: 19114987 Free PMC article.
Cerebellar telomere length and psychiatric disorders.
Zhang D, Cheng L, Craig DW, Redman M, Liu C. Zhang D, et al. Among authors: cheng l. Behav Genet. 2010 Mar;40(2):250-4. doi: 10.1007/s10519-010-9338-0. Epub 2010 Feb 3. Behav Genet. 2010. PMID: 20127402 Free PMC article.
Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.
Gamazon ER, Badner JA, Cheng L, Zhang C, Zhang D, Cox NJ, Gershon ES, Kelsoe JR, Greenwood TA, Nievergelt CM, Chen C, McKinney R, Shilling PD, Schork NJ, Smith EN, Bloss CS, Nurnberger JI, Edenberg HJ, Foroud T, Koller DL, Scheftner WA, Coryell W, Rice J, Lawson WB, Nwulia EA, Hipolito M, Byerley W, McMahon FJ, Schulze TG, Berrettini WH, Potash JB, Zandi PP, Mahon PB, McInnis MG, Zöllner S, Zhang P, Craig DW, Szelinger S, Barrett TB, Liu C. Gamazon ER, et al. Among authors: cheng l. Mol Psychiatry. 2013 Mar;18(3):340-6. doi: 10.1038/mp.2011.174. Epub 2012 Jan 3. Mol Psychiatry. 2013. PMID: 22212596 Free PMC article.
Two gene co-expression modules differentiate psychotics and controls.
Chen C, Cheng L, Grennan K, Pibiri F, Zhang C, Badner JA; Members of the Bipolar Disorder Genome Study (BiGS) Consortium; Gershon ES, Liu C. Chen C, et al. Among authors: cheng l. Mol Psychiatry. 2013 Dec;18(12):1308-14. doi: 10.1038/mp.2012.146. Epub 2012 Nov 13. Mol Psychiatry. 2013. PMID: 23147385 Free PMC article.
Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder.
Lencz T, Guha S, Liu C, Rosenfeld J, Mukherjee S, DeRosse P, John M, Cheng L, Zhang C, Badner JA, Ikeda M, Iwata N, Cichon S, Rietschel M, Nöthen MM, Cheng AT, Hodgkinson C, Yuan Q, Kane JM, Lee AT, Pisanté A, Gregersen PK, Pe'er I, Malhotra AK, Goldman D, Darvasi A. Lencz T, et al. Among authors: cheng l, cheng at. Nat Commun. 2013;4:2739. doi: 10.1038/ncomms3739. Nat Commun. 2013. PMID: 24253340 Free PMC article.
The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders.
Chen C, Meng Q, Xia Y, Ding C, Wang L, Dai R, Cheng L, Gunaratne P, Gibbs RA, Min S, Coarfa C, Reid JG, Zhang C, Jiao C, Jiang Y, Giase G, Thomas A, Fitzgerald D, Brunetti T, Shieh A, Xia C, Wang Y, Wang Y, Badner JA, Gershon ES, White KP, Liu C. Chen C, et al. Among authors: cheng l. Sci Transl Med. 2018 Dec 19;10(472):eaat8178. doi: 10.1126/scitranslmed.aat8178. Epub 2018 Dec 13. Sci Transl Med. 2018. PMID: 30545964 Free PMC article.
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