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Page 1
Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).
Han S, Kim-Howard X, Deshmukh H, Kamatani Y, Viswanathan P, Guthridge JM, Thomas K, Kaufman KM, Ojwang J, Rojas-Villarraga A, Baca V, Orozco L, Rhodes B, Choi CB, Gregersen PK, Merrill JT, James JA, Gaffney PM, Moser KL, Jacob CO, Kimberly RP, Harley JB, Bae SC, Anaya JM, Alarcón-Riquelme ME, Matsuda K, Vyse TJ, Nath SK. Han S, et al. Among authors: gregersen pk. Hum Mol Genet. 2009 Mar 15;18(6):1171-80. doi: 10.1093/hmg/ddp007. Epub 2009 Jan 6. Hum Mol Genet. 2009. PMID: 19129174 Free PMC article.
Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus.
Graham RR, Ortmann WA, Langefeld CD, Jawaheer D, Selby SA, Rodine PR, Baechler EC, Rohlf KE, Shark KB, Espe KJ, Green LE, Nair RP, Stuart PE, Elder JT, King RA, Moser KL, Gaffney PM, Bugawan TL, Erlich HA, Rich SS, Gregersen PK, Behrens TW. Graham RR, et al. Among authors: gregersen pk. Am J Hum Genet. 2002 Sep;71(3):543-53. doi: 10.1086/342290. Epub 2002 Jul 26. Am J Hum Genet. 2002. PMID: 12145745 Free PMC article.
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
Kyogoku C, Langefeld CD, Ortmann WA, Lee A, Selby S, Carlton VE, Chang M, Ramos P, Baechler EC, Batliwalla FM, Novitzke J, Williams AH, Gillett C, Rodine P, Graham RR, Ardlie KG, Gaffney PM, Moser KL, Petri M, Begovich AB, Gregersen PK, Behrens TW. Kyogoku C, et al. Among authors: gregersen pk. Am J Hum Genet. 2004 Sep;75(3):504-7. doi: 10.1086/423790. Epub 2004 Jul 23. Am J Hum Genet. 2004. PMID: 15273934 Free PMC article.
Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.
Criswell LA, Pfeiffer KA, Lum RF, Gonzales B, Novitzke J, Kern M, Moser KL, Begovich AB, Carlton VE, Li W, Lee AT, Ortmann W, Behrens TW, Gregersen PK. Criswell LA, et al. Among authors: gregersen pk. Am J Hum Genet. 2005 Apr;76(4):561-71. doi: 10.1086/429096. Epub 2005 Feb 17. Am J Hum Genet. 2005. PMID: 15719322 Free PMC article.
Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus.
Behrens TW, Graham RR, Kyogoku C, Baechler EC, Ramos PS, Gillett C, Bauer J, Ortmann WA, Hippen KL, Peterson E, Langefeld CD, Moser KL, Gaffney PM, Gregersen PK. Behrens TW, et al. Among authors: gregersen pk. Novartis Found Symp. 2005;267:145-60; discussion 160-4. doi: 10.1002/047002139x.ch10. Novartis Found Symp. 2005. PMID: 15999805
Examination of ancestry and ethnic affiliation using highly informative diallelic DNA markers: application to diverse and admixed populations and implications for clinical epidemiology and forensic medicine.
Yang N, Li H, Criswell LA, Gregersen PK, Alarcon-Riquelme ME, Kittles R, Shigeta R, Silva G, Patel PI, Belmont JW, Seldin MF. Yang N, et al. Among authors: gregersen pk. Hum Genet. 2005 Dec;118(3-4):382-92. doi: 10.1007/s00439-005-0012-1. Epub 2005 Sep 29. Hum Genet. 2005. PMID: 16193326
Genome-wide meta-analysis for rheumatoid arthritis.
Etzel CJ, Chen WV, Shepard N, Jawaheer D, Cornelis F, Seldin MF, Gregersen PK, Amos CI; North American Rheumatoid Arthritis Consortium. Etzel CJ, et al. Among authors: gregersen pk. Hum Genet. 2006 Jul;119(6):634-41. doi: 10.1007/s00439-006-0171-8. Epub 2006 Apr 13. Hum Genet. 2006. PMID: 16612613
Gene expression profiling in human autoimmunity.
Baechler EC, Batliwalla FM, Reed AM, Peterson EJ, Gaffney PM, Moser KL, Gregersen PK, Behrens TW. Baechler EC, et al. Among authors: gregersen pk. Immunol Rev. 2006 Apr;210:120-37. doi: 10.1111/j.0105-2896.2006.00367.x. Immunol Rev. 2006. PMID: 16623768 Review.
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus.
Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, Bauer JW, Ortmann WA, Koeuth T, González Escribano MF; Argentine and Spanish Collaborative Groups; Pons-Estel B, Petri M, Daly M, Gregersen PK, Martín J, Altshuler D, Behrens TW, Alarcón-Riquelme ME. Graham RR, et al. Among authors: gregersen pk. Nat Genet. 2006 May;38(5):550-5. doi: 10.1038/ng1782. Epub 2006 Apr 16. Nat Genet. 2006. PMID: 16642019
Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE.
Graham RR, Ortmann W, Rodine P, Espe K, Langefeld C, Lange E, Williams A, Beck S, Kyogoku C, Moser K, Gaffney P, Gregersen PK, Criswell LA, Harley JB, Behrens TW. Graham RR, et al. Among authors: gregersen pk. Eur J Hum Genet. 2007 Aug;15(8):823-30. doi: 10.1038/sj.ejhg.5201827. Epub 2007 Apr 4. Eur J Hum Genet. 2007. PMID: 17406641
439 results