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Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1.
Brumme ZL, Brumme CJ, Heckerman D, Korber BT, Daniels M, Carlson J, Kadie C, Bhattacharya T, Chui C, Szinger J, Mo T, Hogg RS, Montaner JS, Frahm N, Brander C, Walker BD, Harrigan PR. Brumme ZL, et al. Among authors: harrigan pr. PLoS Pathog. 2007 Jul;3(7):e94. doi: 10.1371/journal.ppat.0030094. PLoS Pathog. 2007. PMID: 17616974 Free PMC article.
HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins.
Brumme ZL, John M, Carlson JM, Brumme CJ, Chan D, Brockman MA, Swenson LC, Tao I, Szeto S, Rosato P, Sela J, Kadie CM, Frahm N, Brander C, Haas DW, Riddler SA, Haubrich R, Walker BD, Harrigan PR, Heckerman D, Mallal S. Brumme ZL, et al. Among authors: harrigan pr. PLoS One. 2009 Aug 19;4(8):e6687. doi: 10.1371/journal.pone.0006687. PLoS One. 2009. PMID: 19690614 Free PMC article.
Viral adaptation to immune selection pressure by HLA class I-restricted CTL responses targeting epitopes in HIV frameshift sequences.
Berger CT, Carlson JM, Brumme CJ, Hartman KL, Brumme ZL, Henry LM, Rosato PC, Piechocka-Trocha A, Brockman MA, Harrigan PR, Heckerman D, Kaufmann DE, Brander C. Berger CT, et al. Among authors: harrigan pr. J Exp Med. 2010 Jan 18;207(1):61-75. doi: 10.1084/jem.20091808. Epub 2010 Jan 11. J Exp Med. 2010. PMID: 20065065 Free PMC article.
Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection.
Brockman MA, Brumme ZL, Brumme CJ, Miura T, Sela J, Rosato PC, Kadie CM, Carlson JM, Markle TJ, Streeck H, Kelleher AD, Markowitz M, Jessen H, Rosenberg E, Altfeld M, Harrigan PR, Heckerman D, Walker BD, Allen TM. Brockman MA, et al. Among authors: harrigan pr. J Virol. 2010 Nov;84(22):11937-49. doi: 10.1128/JVI.01086-10. Epub 2010 Sep 1. J Virol. 2010. PMID: 20810731 Free PMC article.
Population-Level Immune-Mediated Adaptation in HIV-1 Polymerase during the North American Epidemic.
Kinloch NN, MacMillan DR, Le AQ, Cotton LA, Bangsberg DR, Buchbinder S, Carrington M, Fuchs J, Harrigan PR, Koblin B, Kushel M, Markowitz M, Mayer K, Milloy MJ, Schechter MT, Wagner T, Walker BD, Carlson JM, Poon AF, Brumme ZL. Kinloch NN, et al. Among authors: harrigan pr. J Virol. 2015 Nov 11;90(3):1244-58. doi: 10.1128/JVI.02353-15. Print 2016 Feb 1. J Virol. 2015. PMID: 26559841 Free PMC article.
Genotypic and Mechanistic Characterization of Subtype-Specific HIV Adaptation to Host Cellular Immunity.
Kinloch NN, Lee GQ, Carlson JM, Jin SW, Brumme CJ, Byakwaga H, Muzoora C, Bwana MB, Cobarrubias KD, Hunt PW, Martin JN, Carrington M, Bangsberg DR, Harrigan PR, Brockman MA, Brumme ZL. Kinloch NN, et al. Among authors: harrigan pr. J Virol. 2018 Dec 10;93(1):e01502-18. doi: 10.1128/JVI.01502-18. Print 2019 Jan 1. J Virol. 2018. PMID: 30305354 Free PMC article.
321 results