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Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology.
Heymans S, Hirsch E, Anker SD, Aukrust P, Balligand JL, Cohen-Tervaert JW, Drexler H, Filippatos G, Felix SB, Gullestad L, Hilfiker-Kleiner D, Janssens S, Latini R, Neubauer G, Paulus WJ, Pieske B, Ponikowski P, Schroen B, Schultheiss HP, Tschöpe C, Van Bilsen M, Zannad F, McMurray J, Shah AM. Heymans S, et al. Eur J Heart Fail. 2009 Feb;11(2):119-29. doi: 10.1093/eurjhf/hfn043. Eur J Heart Fail. 2009. PMID: 19168509 Free PMC article. Review.
Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy.
Schroen B, Heymans S, Sharma U, Blankesteijn WM, Pokharel S, Cleutjens JP, Porter JG, Evelo CT, Duisters R, van Leeuwen RE, Janssen BJ, Debets JJ, Smits JF, Daemen MJ, Crijns HJ, Bornstein P, Pinto YM. Schroen B, et al. Among authors: heymans s. Circ Res. 2004 Sep 3;95(5):515-22. doi: 10.1161/01.RES.0000141019.20332.3e. Epub 2004 Jul 29. Circ Res. 2004. PMID: 15284191
Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart.
Heymans S, Schroen B, Vermeersch P, Milting H, Gao F, Kassner A, Gillijns H, Herijgers P, Flameng W, Carmeliet P, Van de Werf F, Pinto YM, Janssens S. Heymans S, et al. Circulation. 2005 Aug 23;112(8):1136-44. doi: 10.1161/CIRCULATIONAHA.104.516963. Epub 2005 Aug 15. Circulation. 2005. PMID: 16103240
Imatinib attenuates end-organ damage in hypertensive homozygous TGR(mRen2)27 rats.
Schellings MW, Baumann M, van Leeuwen RE, Duisters RF, Janssen SH, Schroen B, Peutz-Kootstra CJ, Heymans S, Pinto YM. Schellings MW, et al. Among authors: heymans s. Hypertension. 2006 Mar;47(3):467-74. doi: 10.1161/01.HYP.0000202487.68969.f7. Epub 2006 Jan 23. Hypertension. 2006. PMID: 16432052
Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis.
Heymans S, Pauschinger M, De Palma A, Kallwellis-Opara A, Rutschow S, Swinnen M, Vanhoutte D, Gao F, Torpai R, Baker AH, Padalko E, Neyts J, Schultheiss HP, Van de Werf F, Carmeliet P, Pinto YM. Heymans S, et al. Circulation. 2006 Aug 8;114(6):565-73. doi: 10.1161/CIRCULATIONAHA.105.591032. Epub 2006 Jul 31. Circulation. 2006. PMID: 16880329
How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology.
Paulus WJ, Tschöpe C, Sanderson JE, Rusconi C, Flachskampf FA, Rademakers FE, Marino P, Smiseth OA, De Keulenaer G, Leite-Moreira AF, Borbély A, Edes I, Handoko ML, Heymans S, Pezzali N, Pieske B, Dickstein K, Fraser AG, Brutsaert DL. Paulus WJ, et al. Among authors: heymans s. Eur Heart J. 2007 Oct;28(20):2539-50. doi: 10.1093/eurheartj/ehm037. Epub 2007 Apr 11. Eur Heart J. 2007. PMID: 17428822
Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy.
Schroen B, Leenders JJ, van Erk A, Bertrand AT, van Loon M, van Leeuwen RE, Kubben N, Duisters RF, Schellings MW, Janssen BJ, Debets JJ, Schwake M, Høydal MA, Heymans S, Saftig P, Pinto YM. Schroen B, et al. Among authors: heymans s. J Exp Med. 2007 May 14;204(5):1227-35. doi: 10.1084/jem.20070145. Epub 2007 May 7. J Exp Med. 2007. PMID: 17485520 Free PMC article.
Acute viral myocarditis.
Dennert R, Crijns HJ, Heymans S. Dennert R, et al. Among authors: heymans s. Eur Heart J. 2008 Sep;29(17):2073-82. doi: 10.1093/eurheartj/ehn296. Epub 2008 Jul 9. Eur Heart J. 2008. PMID: 18617482 Free PMC article. Review.
miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling.
Duisters RF, Tijsen AJ, Schroen B, Leenders JJ, Lentink V, van der Made I, Herias V, van Leeuwen RE, Schellings MW, Barenbrug P, Maessen JG, Heymans S, Pinto YM, Creemers EE. Duisters RF, et al. Among authors: heymans s. Circ Res. 2009 Jan 30;104(2):170-8, 6p following 178. doi: 10.1161/CIRCRESAHA.108.182535. Epub 2008 Dec 18. Circ Res. 2009. PMID: 19096030
Absence of thrombospondin-2 causes age-related dilated cardiomyopathy.
Swinnen M, Vanhoutte D, Van Almen GC, Hamdani N, Schellings MW, D'hooge J, Van der Velden J, Weaver MS, Sage EH, Bornstein P, Verheyen FK, VandenDriessche T, Chuah MK, Westermann D, Paulus WJ, Van de Werf F, Schroen B, Carmeliet P, Pinto YM, Heymans S. Swinnen M, et al. Among authors: heymans s. Circulation. 2009 Oct 20;120(16):1585-97. doi: 10.1161/CIRCULATIONAHA.109.863266. Epub 2009 Oct 5. Circulation. 2009. PMID: 19805649 Free article.
340 results