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Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells.
Yu JJ, Robb VA, Morrison TA, Ariazi EA, Karbowniczek M, Astrinidis A, Wang C, Hernandez-Cuebas L, Seeholzer LF, Nicolas E, Hensley H, Jordan VC, Walker CL, Henske EP. Yu JJ, et al. Among authors: walker cl. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2635-40. doi: 10.1073/pnas.0810790106. Epub 2009 Feb 6. Proc Natl Acad Sci U S A. 2009. PMID: 19202070 Free PMC article.
Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM).
Goncharova EA, Goncharov DA, Eszterhas A, Hunter DS, Glassberg MK, Yeung RS, Walker CL, Noonan D, Kwiatkowski DJ, Chou MM, Panettieri RA Jr, Krymskaya VP. Goncharova EA, et al. Among authors: walker cl. J Biol Chem. 2002 Aug 23;277(34):30958-67. doi: 10.1074/jbc.M202678200. Epub 2002 Jun 3. J Biol Chem. 2002. PMID: 12045200 Free article.
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL. Alexander A, et al. Among authors: walker cl. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4153-8. doi: 10.1073/pnas.0913860107. Epub 2010 Feb 16. Proc Natl Acad Sci U S A. 2010. PMID: 20160076 Free PMC article.
297 results