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Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.
Devy L, Huang L, Naa L, Yanamandra N, Pieters H, Frans N, Chang E, Tao Q, Vanhove M, Lejeune A, van Gool R, Sexton DJ, Kuang G, Rank D, Hogan S, Pazmany C, Ma YL, Schoonbroodt S, Nixon AE, Ladner RC, Hoet R, Henderikx P, Tenhoor C, Rabbani SA, Valentino ML, Wood CR, Dransfield DT. Devy L, et al. Among authors: hoet r. Cancer Res. 2009 Feb 15;69(4):1517-26. doi: 10.1158/0008-5472.CAN-08-3255. Epub 2009 Feb 10. Cancer Res. 2009. PMID: 19208838
Screening isolates from antibody phage-display libraries.
Buckler DR, Park A, Viswanathan M, Hoet RM, Ladner RC. Buckler DR, et al. Among authors: hoet rm. Drug Discov Today. 2008 Apr;13(7-8):318-24. doi: 10.1016/j.drudis.2007.10.012. Epub 2007 Nov 26. Drug Discov Today. 2008. PMID: 18405844 Review.
Oligonucleotide-assisted cleavage and ligation: a novel directional DNA cloning technology to capture cDNAs. Application in the construction of a human immune antibody phage-display library.
Schoonbroodt S, Frans N, DeSouza M, Eren R, Priel S, Brosh N, Ben-Porath J, Zauberman A, Ilan E, Dagan S, Cohen EH, Hoogenboom HR, Ladner RC, Hoet RM. Schoonbroodt S, et al. Among authors: hoet rm. Nucleic Acids Res. 2005 May 19;33(9):e81. doi: 10.1093/nar/gni080. Nucleic Acids Res. 2005. PMID: 15905471 Free PMC article.
Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity.
Hoet RM, Cohen EH, Kent RB, Rookey K, Schoonbroodt S, Hogan S, Rem L, Frans N, Daukandt M, Pieters H, van Hegelsom R, Neer NC, Nastri HG, Rondon IJ, Leeds JA, Hufton SE, Huang L, Kashin I, Devlin M, Kuang G, Steukers M, Viswanathan M, Nixon AE, Sexton DJ, Hoogenboom HR, Ladner RC. Hoet RM, et al. Nat Biotechnol. 2005 Mar;23(3):344-8. doi: 10.1038/nbt1067. Epub 2005 Feb 20. Nat Biotechnol. 2005. PMID: 15723048
Antibody phage display technology and its applications.
Hoogenboom HR, de Bruïne AP, Hufton SE, Hoet RM, Arends JW, Roovers RC. Hoogenboom HR, et al. Among authors: hoet rm. Immunotechnology. 1998 Jun;4(1):1-20. doi: 10.1016/s1380-2933(98)00007-4. Immunotechnology. 1998. PMID: 9661810 Review.
Development of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell-mediated antitumor immune response.
De Gassart A, Le KS, Brune P, Agaugué S, Sims J, Goubard A, Castellano R, Joalland N, Scotet E, Collette Y, Valentin E, Ghigo C, Pasero C, Colazet M, Guillén J, Cano CE, Marabelle A, De Bonno J, Hoet R, Truneh A, Olive D, Frohna P. De Gassart A, et al. Among authors: hoet r. Sci Transl Med. 2021 Oct 20;13(616):eabj0835. doi: 10.1126/scitranslmed.abj0835. Epub 2021 Oct 20. Sci Transl Med. 2021. PMID: 34669444
BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells.
Cano CE, Pasero C, De Gassart A, Kerneur C, Gabriac M, Fullana M, Granarolo E, Hoet R, Scotet E, Rafia C, Herrmann T, Imbert C, Gorvel L, Vey N, Briantais A, le Floch AC, Olive D. Cano CE, et al. Among authors: hoet r. Cell Rep. 2021 Jul 13;36(2):109359. doi: 10.1016/j.celrep.2021.109359. Cell Rep. 2021. PMID: 34260935 Free article.
36 results