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Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.
Devy L, Huang L, Naa L, Yanamandra N, Pieters H, Frans N, Chang E, Tao Q, Vanhove M, Lejeune A, van Gool R, Sexton DJ, Kuang G, Rank D, Hogan S, Pazmany C, Ma YL, Schoonbroodt S, Nixon AE, Ladner RC, Hoet R, Henderikx P, Tenhoor C, Rabbani SA, Valentino ML, Wood CR, Dransfield DT. Devy L, et al. Among authors: ladner rc. Cancer Res. 2009 Feb 15;69(4):1517-26. doi: 10.1158/0008-5472.CAN-08-3255. Epub 2009 Feb 10. Cancer Res. 2009. PMID: 19208838
Identification and characterization of a human monoclonal antagonistic antibody AL-57 that preferentially binds the high-affinity form of lymphocyte function-associated antigen-1.
Huang L, Shimaoka M, Rondon IJ, Roy I, Chang Q, Po M, Dransfield DT, Ladner RC, Edge AS, Salas A, Wood CR, Springer TA, Cohen EH. Huang L, et al. Among authors: ladner rc. J Leukoc Biol. 2006 Oct;80(4):905-14. doi: 10.1189/jlb.1105649. Epub 2006 Aug 3. J Leukoc Biol. 2006. PMID: 16888085 Free PMC article.
Screening isolates from antibody phage-display libraries.
Buckler DR, Park A, Viswanathan M, Hoet RM, Ladner RC. Buckler DR, et al. Among authors: ladner rc. Drug Discov Today. 2008 Apr;13(7-8):318-24. doi: 10.1016/j.drudis.2007.10.012. Epub 2007 Nov 26. Drug Discov Today. 2008. PMID: 18405844 Review.
Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
Kenniston JA, Faucette RR, Martik D, Comeau SR, Lindberg AP, Kopacz KJ, Conley GP, Chen J, Viswanathan M, Kastrapeli N, Cosic J, Mason S, DiLeo M, Abendroth J, Kuzmic P, Ladner RC, Edwards TE, TenHoor C, Adelman BA, Nixon AE, Sexton DJ. Kenniston JA, et al. Among authors: ladner rc. J Biol Chem. 2014 Aug 22;289(34):23596-608. doi: 10.1074/jbc.M114.569061. Epub 2014 Jun 26. J Biol Chem. 2014. PMID: 24970892 Free PMC article.
46 results